Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 8/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7333599 | 0.96 | HDAC1 (0.53) | EPHX1EPHX2HDAC1HDAC2ALDH1A1 | |
| SCHEMBL7331245 | 0.92 | KMT2A (0.54) | EPHX1MAPT | |
| SCHEMBL7331228 | 0.87 | KMT2A (0.52) | HTTMAPT | |
| SCHEMBL7337841 | 0.83 | THRA (0.54) | EPHX2ALDH1A1HTTLMNA | |
| SCHEMBL7335188 | 0.82 | THRA (0.53) | EPHX2ALDH1A1HTTLMNA | |
| SCHEMBL7340472 | 0.82 | THRA (0.53) | EPHX2ALDH1A1HTTLMNA | |
| SCHEMBL7337979 | 0.82 | ALDH1A1 (0.54) | ALDH1A1HTTMAPTLMNA | |
| SCHEMBL7333819 | 0.80 | RAB9A (0.67) | ALDH1A1HTTMAPTLMNA | |
| SCHEMBL7157554 | 0.80 | EPHX1 (0.67) | EPHX1EPHX2HDAC1HDAC2ALDH1A1 | |
| SCHEMBL7331661 | 0.80 | ALDH1A1 (0.57) | ALDH1A1HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0475531-B1 | Benzoic acid phenylester compounds and elastase inhibiting compositions containing the same | ASAHI CHEMICAL IND (JP) | 1995-01-18 | — | — | EP | disclosed |
| EP-0475531-A1 | Benzoic acid phenylester compounds and elastase inhibiting compositions containing the same | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1992-03-18 | — | — | EP | disclosed |