Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL1RN | P18510 | 1/20 | 0.53 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.53 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.53 |
| ▸ | REN | P00797 | 2/20 | 0.53 |
| ▸ | MME | P08473 | 1/20 | 0.51 |
| ▸ | ACE | P12821 | 1/20 | 0.51 |
| ▸ | CPA1 | P15085 | 1/20 | 0.51 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | LTA4H | P09960 | 4/20 | 0.46 |
| ▸ | BCL2 | P10415 | 1/20 | 0.45 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.45 |
| ▸ | YAP1 | P46937 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7346037 | 1.00 | IL1RN (0.53) | IL1RNERAP2ERAP1RENMME | |
| SCHEMBL7338162 | 0.91 | MME (0.56) | IL1RNERAP2ERAP1RENMME | |
| SCHEMBL7341980 | 0.89 | MME (0.52) | IL1RNERAP2ERAP1RENMME | |
| SCHEMBL7346541 | 0.89 | REN (0.47) | IL1RNERAP2ERAP1RENMME | |
| SCHEMBL7345226 | 0.85 | IL1RN (0.55) | IL1RNERAP2ERAP1RENMME | |
| SCHEMBL7344077 | 0.85 | PPARG (0.60) | IL1RNERAP2ERAP1MMEACE | |
| SCHEMBL7338616 | 0.85 | IL1RN (0.56) | IL1RNERAP2ERAP1RENMME | |
| SCHEMBL7341943 | 0.85 | CTSS (0.53) | IL1RNERAP2ERAP1RENMME | |
| SCHEMBL7338772 | 0.85 | IL1RN (0.56) | IL1RNERAP2ERAP1RENMME | |
| SCHEMBL7337028 | 0.84 | PSMB1 (0.58) | IL1RNERAP2ERAP1MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | disclosed |