Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | GSK3A | P49840 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11353245 | 0.82 | TP53 (0.33) | TP53NR1H2NR1H3TSHRKDM4E | |
| SCHEMBL28533392 | 0.82 | L3MBTL1 (0.44) | — | |
| SCHEMBL7337040 | 0.81 | SLC2A1 (0.36) | KDM4ELMNACYP19A1 | |
| SCHEMBL1271761 | 0.81 | TP53 (0.42) | TP53NR1H2NR1H3TSHRKDM4E | |
| SCHEMBL11363391 | 0.80 | ALDH1A1 (0.43) | TP53NR1H2NR1H3TSHRKDM4E | |
| SCHEMBL9076841 | 0.79 | TP53 (0.40) | TP53NR1H2NR1H3TSHRKDM4E | |
| SCHEMBL1107767 | 0.78 | TP53 (0.48) | TP53NR1H2NR1H3TSHRKDM4E | |
| SCHEMBL9631874 | 0.77 | POLB (0.35) | KDM4E | |
| SCHEMBL9074360 | 0.75 | TDP1 (0.44) | TP53NR1H2NR1H3TSHRCALM1 | |
| SCHEMBL11365347 | 0.74 | MAPT (0.53) | TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0468825-B1 | Organosilane derivatives, pharmaceutical compositions containing them and process for preparing same | RICHTER GEDEON VEGYESZET (HU) | 1997-01-08 | — | — | EP | disclosed |
| US-5340823-A | Administering a muscle relaxants for treating parkinson*s disease | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1994-08-23 | — | — | US | disclosed |
| US-5198446-A | Muscle Relaxants | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1993-03-30 | — | — | US | disclosed |
| EP-0468825-A1 | Organosilane derivatives, pharmaceutical compositions containing them and process for preparing same | Richter Gedeon Vegyészeti Gyár R.T. (HU) | 1992-01-29 | — | — | EP | disclosed |