SCHEMBL28533392

SCHEMBL28533392

C[Si](C)(CCCc1ccccc1)Cc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
SIGMAR1 Q99720 5/20 0.43
MAOA P21397 1/20 0.43
CHRM2 P08172 1/20 0.42
HTR1A P08908 1/20 0.42
ADRA2A P08913 1/20 0.42
CHRM1 P11229 1/20 0.42
DRD1 P21728 1/20 0.42
SLC6A2 P23975 1/20 0.42
SLC6A4 P31645 1/20 0.42
ADRA1A P35348 1/20 0.42
OPRM1 P35372 1/20 0.42
DRD3 P35462 1/20 0.42
SLC6A3 Q01959 1/20 0.42
KCNH2 Q12809 1/20 0.42
AOC3 Q16853 1/20 0.42
MAOB P27338 1/20 0.42
HTR2A P28223 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14838178 0.83 CHRM2 (0.47) L3MBTL1MEN1KMT2ASIGMAR1MAOA
SCHEMBL11363391 0.82 ALDH1A1 (0.43) L3MBTL1MEN1KMT2A
SCHEMBL7338237 0.82 TP53 (0.34)
SCHEMBL16216219 0.80 L3MBTL1 (0.48) L3MBTL1MEN1KMT2ASIGMAR1MAOA
SCHEMBL1107767 0.79 TP53 (0.48) MAOASLC6A2SLC6A4SLC6A3MAOB
SCHEMBL23532521 0.78 SIGMAR1 (0.46) L3MBTL1SIGMAR1MAOAADRA1ASLC6A3
SCHEMBL28103762 0.78 TP53 (0.44) SIGMAR1
SCHEMBL523288 0.77 L3MBTL1 (0.45) L3MBTL1MEN1KMT2ASIGMAR1MAOA
SCHEMBL9074360 0.77 TDP1 (0.44)
SCHEMBL524107 0.77 L3MBTL1 (0.45) L3MBTL1MEN1KMT2ASIGMAR1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110343128-B Method for preparing silane through hydrosilation reaction 中国科学院化学研究所 2021-02-19 CN disclosed