Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11626081 | 1.00 | TSHR (0.36) | TSHRSMN1; SMN2PIK3CDPIK3CAPIK3CB | |
| SCHEMBL395804 | 1.00 | TSHR (0.36) | TSHRSMN1; SMN2PIK3CDPIK3CAPIK3CB | |
| SCHEMBL194872 | 0.97 | TSHR (0.38) | TSHRSMN1; SMN2PIK3CDPIK3CAPIK3CB | |
| SCHEMBL20072016 | 0.95 | TSHR (0.36) | TSHRSMN1; SMN2 | |
| SCHEMBL2761366 | 0.92 | TSHR (0.38) | TSHR | |
| SCHEMBL286913 | 0.86 | TSHR (0.42) | TSHR | |
| SCHEMBL16227572 | 0.84 | TSHR (0.40) | TSHR | |
| SCHEMBL28735623 | 0.82 | ALDH1A1 (0.36) | TSHR | |
| SCHEMBL16379395 | 0.81 | — | — | |
| SCHEMBL2915774 | 0.80 | TSHR (0.47) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4228179-A | ANTICONVULSANTS | WARNER-LAMBERT COMPANY (US) | 1980-10-14 | — | — | US | disclosed |
| US-4152326-A | AND CYCLIC HYDROXYIMIDES, INTERMEDIATES IN PREPARATION OF CYCLIC AMINO ACIDS | WARNER-LAMBERT COMPANY (US) | 1979-05-01 | — | — | US | disclosed |
| US-4087544-A | Treatment of cranial dysfunctions using novel cyclic amino acids | WARNER-LAMBERT COMPANY (US) | 1978-05-02 | — | — | US | disclosed |
| US-4024175-A | Cyclic amino acids | WARNER-LAMBERT COMPANY (US) | 1977-05-17 | — | — | US | disclosed |