SCHEMBL395804

SCHEMBL395804

O=C1CC2(CCCCC2)CC(=O)O1

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.32
PIK3CD O00329 1/20 0.32
PIK3CA P42336 1/20 0.32
PIK3CB P42338 1/20 0.32
PIK3CG P48736 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11626081 1.00 TSHR (0.36) TSHRSMN1; SMN2PIK3CDPIK3CAPIK3CB
SCHEMBL7338345 1.00 TSHR (0.36) TSHRSMN1; SMN2PIK3CDPIK3CAPIK3CB
SCHEMBL194872 0.97 TSHR (0.38) TSHRSMN1; SMN2PIK3CDPIK3CAPIK3CB
SCHEMBL20072016 0.95 TSHR (0.36) TSHRSMN1; SMN2
SCHEMBL2761366 0.92 TSHR (0.38) TSHR
SCHEMBL286913 0.86 TSHR (0.42) TSHR
SCHEMBL16227572 0.84 TSHR (0.40) TSHR
SCHEMBL28735623 0.82 ALDH1A1 (0.36) TSHR
SCHEMBL16379395 0.81
SCHEMBL2915774 0.80 TSHR (0.47) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 298 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121574543-A Carbon fiber reinforced nylon material and preparation method thereof 苏州润佳高分子材料有限公司 2026-02-27 CN claimed
CN-117924901-A Spraying-free ultra-low gloss PC/ABS alloy material and preparation method thereof 苏州润佳工程塑料股份有限公司 2024-04-26 CN claimed
CN-115850109-A CAM preparation process and application thereof 河北三川化工有限公司 2023-03-28 CN claimed
CN-109232508-B Preparation method of 1, 1-cyclohexyl diacetic anhydride 河北三川化工有限公司 2022-05-27 CN claimed
CN-215139877-U Ammoniation reaction device 河北三川化工有限公司 2021-12-14 CN claimed
CN-113444011-A Preparation method and application of 1, 1-cyclohexane-diacetic acid monoamide 江西同和药业股份有限公司 2021-09-28 CN claimed
CN-112574100-A Preparation method of glutarimide derivative 南京德尔诺医药科技有限公司 2021-03-30 CN claimed
CN-103576461-A Photosensitive resin composition, colored filter, liquid crystal display device and imaging element DONGWOO FINE CHEM CO LTD 2014-02-12 CN claimed
CN-103509151-A Alkali soluble resin and photosensitive resin composition containing the same DONGWOO FINE CHEM CO LTD 2014-01-15 CN claimed
EP-1682488-B1 PROCESS FOR THE PREPARATION OF GABAPENTIN ZACH SYSTEM SPA (IT) 2013-01-02 EP claimed
CN-101037395-A Preparation method of 1,1-Cyclohexane diethyl acid mono amide CHIRAL MEDICINE CHEMICALS CO L (CN) 2007-09-19 CN claimed
US-20070066843-A1 Process for the preparation of gabapentin ZACH SYSTEM S.P.A. (IT) 2007-03-22 US claimed
EP-1682488-A2 PROCESS FOR THE PREPARATION OF GABAPENTIN ZAMBON GROUP S.p.A. (IT) 2006-07-26 EP claimed
WO-2005044779-A2 PROCESS FOR THE PREPARATION OF GABAPENTIN ZAMBON GROUP S.P.A. (IT) 2005-05-19 WO claimed
WO-2003002517-A1 PROCESS FOR THE PREPARATION OF 1.1-CYCLOHEXANE DIACETIC ACID MONOAMIDE BROMINE COMPOUNDS LTD. (IL) 2003-01-09 WO claimed
EP-0755375-B1 AQUEOUS PROCESS FOR PREPARING AMIDO-CARBOXYLIC ACIDS BY REACTING AN AMINO ACID WITH A CARBOXYLIC ACID ANHYDRIDE EASTMAN CHEM CO (US) 1999-10-13 EP claimed
CN-1146198-A Aqueous process for preparing amido-carboxylic acids by reacting amino acids with carboxylic acid anhydrides EASTMAN CHEM CO (US) 1997-03-26 CN claimed
EP-0755375-A1 AQUEOUS PROCESS FOR PREPARING AMIDO-CARBOXYLIC ACIDS BY REACTING AN AMINO ACID WITH A CARBOXYLIC ACID ANHYDRIDE EASTMAN CHEMICAL COMPANY (US) 1997-01-29 EP claimed
WO-1995028381-A1 AQUEOUS PROCESS FOR PREPARING AMIDO-CARBOXYLIC ACIDS BY REACTING AN AMINO ACID WITH A CARBOXYLIC ACID ANHYDRIDE EASTMAN CHEMICAL COMPANY (US) 1995-10-26 WO claimed
US-5391780-A Heating a mixture of water and lactam to hydrolyze; cooling; amididation by a carboxylic anhydride; separation of water and organic layer-containing product EASTMAN CHEMICAL COMPANY (US) 1995-02-21 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070066843-A1 Process for the preparation of gabapentin GABRD, GABRB1, GABRG1 TSHR 4666/4885SMN1; SMN2 1315/4885PIK3CD 712/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.