SCHEMBL194872

SCHEMBL194872

O=C1CC2(CCCC2)CC(=O)O1

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.33
PIK3CD O00329 1/20 0.30
PIK3CA P42336 1/20 0.30
PIK3CB P42338 1/20 0.30
PIK3CG P48736 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11626081 0.97 TSHR (0.36) TSHRSMN1; SMN2PIK3CDPIK3CAPIK3CB
SCHEMBL7338345 0.97 TSHR (0.36) TSHRSMN1; SMN2PIK3CDPIK3CAPIK3CB
SCHEMBL20072016 0.97 TSHR (0.36) TSHRSMN1; SMN2
SCHEMBL395804 0.97 TSHR (0.36) TSHRSMN1; SMN2PIK3CDPIK3CAPIK3CB
SCHEMBL2761366 0.94 TSHR (0.38) TSHR
SCHEMBL286913 0.88 TSHR (0.42) TSHR
SCHEMBL16379395 0.84
SCHEMBL2915774 0.82 TSHR (0.47) TSHR
SCHEMBL16227572 0.82 TSHR (0.40) TSHR
SCHEMBL28735623 0.80 ALDH1A1 (0.36) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 825 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12110390-B2 Solid dispersion, preparation method therefor, chain-extended polyurethane using same, and epoxy resin composition comprising same SAMYANG CORPORATION (KR) 2024-10-08 US claimed
US-11912818-B2 Method for synthesizing aromatic-aliphatic copolyester without catalyst and product thereof ZHEJIANG UNIVERSITY (CN) 2024-02-27 US claimed
EP-4314187-A1 COATING COMPOSITIONS PPG Industries Ohio Inc. (US) 2024-02-07 EP claimed
US-20230391948-A1 METHOD FOR SYNTHESIZING AROMATIC-ALIPHATIC COPOLYESTER WITHOUT CATALYST AND PRODUCT THEREOF ZHEJIANG UNIVERSITY (CN) 2023-12-07 US claimed
EP-4201922-A1 METHOD FOR PURIFYING WASTED SOLUTION COMPRISING N-METHYL-2-PYRROLIDONE JAEWON INDUSTRIAL CO., LTD (KR) 2023-06-28 EP claimed
US-20230192609-A1 METHOD FOR PURIYFING WASTE N-METHYL-2-PYRROLIDONE JAEWON INDUSTRIAL CO., LTD (KR) 2023-06-22 US claimed
US-20230114308-A1 Flux-Compatible Epoxy-Anhydride Adhesives Compositions for Low-Gap Underfill Applications HENKEL AG & CO KGAA (DE) 2023-04-13 US claimed
WO-2022204686-A1 COATING COMPOSITIONS PPG INDUSTRIES OHIO, INC. (US) 2022-09-29 WO claimed
CN-113061212-B Unsaturated polyester resin composition and composite material prepared from same 江苏澳盛复合材料科技有限公司 2022-06-21 CN claimed
US-20220119584-A1 Degradable Urethane and Urethane-Urea Systems LANXESS CORPORATION (US) 2022-04-21 US claimed
US-5929131-A Polymerizable cyclodextrin derivatives AMERICAN DENTAL ASSOCIATION HEALTH FOUNDATION (US) 1999-07-27 US claimed
US-5792821-A Polymerizable cyclodextrin derivatives AMERICAN DENTAL ASSOCIATION HEALTH FOUNDATION (US) 1998-08-11 US claimed
EP-0799016-A1 POLYMERIZABLE COMPOUNDS AND COMPOSITIONS DENTSPLY INTERNATIONAL, INC. (US) 1997-10-08 EP claimed
EP-0743574-A2 Migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
EP-0743573-A2 Method for obtaining image contrast migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
US-5563014-A SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT XEROX CORPORATION (US) 1996-10-08 US claimed
WO-1996019179-A1 POLYMERIZABLE COMPOUNDS AND COMPOSITIONS DENTSPLY INTERNATIONAL INC. (US) 1996-06-27 WO claimed
US-5514505-A SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE XEROX CORPORATION (US) 1996-05-07 US claimed
EP-0674233-A2 Recording sheets XEROX CORPORATION (US) 1995-09-27 EP claimed
EP-0447345-A2 New Azaspyro [4.5] decane-7,9-dione derivatives FABRICA ESPANOLA DE PRODUCTOS QUIMICOS Y FARMACEUTICOS, S.A. (FAES) (ES) 1991-09-18 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230192609-A1 METHOD FOR PURIYFING WASTE N-METHYL-2-PYRROLIDONE NPEPPS, AZI2, ALKBH2 TSHR 4091/4885SMN1; SMN2 771/4885PIK3CD 3605/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.