Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB1 | P20618 | 1/20 | 0.48 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.48 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 6/20 | 0.46 |
| ▸ | CTSS | P25774 | 5/20 | 0.46 |
| ▸ | CTSK | P43235 | 12/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | CASP6 | P55212 | 1/20 | 0.45 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.45 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7344658 | 0.91 | PSMB1 (0.52) | PSMB1PSMB5PSMB2CTSLCTSS | |
| SCHEMBL7345357 | 0.89 | PSMB1 (0.51) | PSMB1PSMB5PSMB2CTSLCTSS | |
| SCHEMBL7334968 | 0.88 | PSMB1 (0.45) | PSMB1PSMB5PSMB2CTSLCTSS | |
| SCHEMBL8395854 | 0.86 | CTSL (0.52) | CTSLCTSSCTSKCASP1CASP3 | |
| SCHEMBL7335464 | 0.82 | PSMB1 (0.46) | PSMB1PSMB5PSMB2CTSLCTSS | |
| SCHEMBL9220584 | 0.82 | PSMB1 (0.46) | PSMB1PSMB5PSMB2CTSLCTSS | |
| SCHEMBL7347438 | 0.82 | PSMB1 (0.43) | PSMB1PSMB5PSMB2CTSLCTSS | |
| SCHEMBL7334429 | 0.77 | PSMB1 (0.50) | PSMB1PSMB5PSMB2CTSLCTSS | |
| SCHEMBL7305711 | 0.75 | CTSL (0.52) | PSMB1PSMB5PSMB2CTSLCTSS | |
| SCHEMBL25949248 | 0.75 | CTSK (0.65) | PSMB1PSMB5PSMB2CTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5416117-A | Protease inhibitor | MITSUBISHI KASEI CORPORATION (JP) | 1995-05-16 | — | — | US | disclosed |
| EP-0520427-B1 | Cyclopropenone derivatives | MITSUBISHI CHEM IND (JP) | 1994-12-14 | — | — | EP | disclosed |
| US-5328909-A | Protease inhibitors | MITSUBISHI KASEI CORPORATION (JP) | 1994-07-12 | — | — | US | disclosed |
| EP-0520427-A1 | Cyclopropenone derivatives | Mitsubishi Chemical Corporation (JP) | 1992-12-30 | — | — | EP | disclosed |