Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB1 | P20618 | 1/20 | 0.52 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.52 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.52 |
| ▸ | CTSK | P43235 | 16/20 | 0.48 |
| ▸ | CTSL | P07711 | 9/20 | 0.47 |
| ▸ | CTSS | P25774 | 8/20 | 0.47 |
| ▸ | CTSB | P07858 | 4/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.46 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7345357 | 0.94 | PSMB1 (0.51) | PSMB1PSMB5PSMB2CTSKCTSL | |
| SCHEMBL7338532 | 0.91 | PSMB1 (0.48) | PSMB1PSMB5PSMB2CTSKCTSL | |
| SCHEMBL7334429 | 0.83 | PSMB1 (0.50) | PSMB1PSMB5PSMB2CTSKCTSL | |
| SCHEMBL7334968 | 0.80 | PSMB1 (0.45) | PSMB1PSMB5PSMB2CTSKCTSL | |
| SCHEMBL13295114 | 0.76 | PSMB1 (0.66) | PSMB1PSMB5PSMB2CTSKCTSL | |
| SCHEMBL8395854 | 0.76 | CTSL (0.52) | CTSKCTSLCTSSCTSBCASP1 | |
| SCHEMBL17596413 | 0.76 | CTSK (0.61) | PSMB1PSMB5PSMB2CTSKCTSL | |
| SCHEMBL17596460 | 0.76 | CTSK (0.61) | PSMB1PSMB5PSMB2CTSKCTSL | |
| SCHEMBL17596461 | 0.76 | CTSK (0.61) | PSMB1PSMB5PSMB2CTSKCTSL | |
| SCHEMBL2724462 | 0.75 | CTSK (0.61) | PSMB1PSMB5PSMB2CTSKCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5416117-A | Protease inhibitor | MITSUBISHI KASEI CORPORATION (JP) | 1995-05-16 | — | — | US | disclosed |
| EP-0520427-B1 | Cyclopropenone derivatives | MITSUBISHI CHEM IND (JP) | 1994-12-14 | — | — | EP | disclosed |
| US-5328909-A | Protease inhibitors | MITSUBISHI KASEI CORPORATION (JP) | 1994-07-12 | — | — | US | disclosed |
| EP-0520427-A1 | Cyclopropenone derivatives | Mitsubishi Chemical Corporation (JP) | 1992-12-30 | — | — | EP | disclosed |