Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 12/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7341000 | 0.85 | BRD4 (0.55) | BRD4TDP1L3MBTL1MEN1KMT2A | |
| SCHEMBL7339795 | 0.81 | SGMS2 (0.57) | BRD4TDP1L3MBTL1MEN1KMT2A | |
| SCHEMBL7342620 | 0.80 | BRD4 (0.50) | BRD4TDP1L3MBTL1MEN1KMT2A | |
| SCHEMBL7344448 | 0.78 | PYGL (0.58) | BRD4TDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL8636250 | 0.78 | BRD4 (0.51) | BRD4MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL7336012 | 0.78 | MEN1 (0.55) | TDP1L3MBTL1MEN1KMT2ASGMS2 | |
| SCHEMBL8636243 | 0.77 | BRD4 (0.49) | BRD4TDP1L3MBTL1MEN1KMT2A | |
| SCHEMBL7340419 | 0.76 | TP53 (0.51) | BRD4TDP1L3MBTL1MEN1KMT2A | |
| SCHEMBL2875064 | 0.76 | KDM4E (0.62) | TDP1L3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL11959268 | 0.76 | BRD4 (0.76) | BRD4MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832061-B1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| US-6054457-A | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-25 | — | — | US | disclosed |
| EP-0832061-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-04-01 | — | — | EP | disclosed |
| WO-1996041795-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-27 | — | — | WO | disclosed |