Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | PPIA | P62937 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7773796 | 0.87 | SGMS2 (0.60) | MEN1KMT2ASGMS2RAB9ACYP1A2 | |
| SCHEMBL7999267 | 0.86 | SGMS2 (0.58) | MEN1KMT2ASGMS2RAB9ACYP1A2 | |
| SCHEMBL8318448 | 0.86 | ALDH1A1 (0.56) | MEN1KMT2ARAB9ACYP1A2KDM4E | |
| SCHEMBL13566602 | 0.85 | SGMS2 (0.52) | MEN1KMT2ASGMS2RAB9ACYP1A2 | |
| SCHEMBL8319324 | 0.84 | RAB9A (0.64) | MEN1KMT2ARAB9ACYP1A2KDM4E | |
| SCHEMBL7334998 | 0.82 | ALDH1A1 (0.65) | MEN1KMT2ARAB9ACYP1A2KDM4E | |
| SCHEMBL8319629 | 0.82 | RAB9A (0.51) | MEN1KMT2ARAB9ACYP1A2KDM4E | |
| SCHEMBL11740137 | 0.81 | MRGPRX4 (0.57) | MEN1KMT2ARAB9AKDM4EALDH1A1 | |
| SCHEMBL3810850 | 0.80 | SGMS2 (0.58) | MEN1KMT2ASGMS2RAB9ACYP1A2 | |
| SCHEMBL8317200 | 0.79 | RAB9A (0.54) | MEN1KMT2ARAB9ACYP1A2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832061-B1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| EP-0832061-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-04-01 | — | — | EP | disclosed |
| WO-1996041795-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-27 | — | — | WO | disclosed |