SCHEMBL733870

SCHEMBL733870

CSc1ccc(C(=O)c2ccc(C)cc2)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.70
LMNA P02545 2/20 0.70
SRD5A2 P31213 2/20 0.59
ATM Q13315 3/20 0.54
NPSR1 Q6W5P4 3/20 0.54
HPGD P15428 2/20 0.54
CYP1A2 P05177 1/20 0.54
CYP3A4 P08684 1/20 0.54
CYP2C9 P11712 1/20 0.54
ALOX15 P16050 1/20 0.54
TSHR P16473 1/20 0.54
NFKB1 P19838 1/20 0.54
PDE4A P27815 1/20 0.54
BLM P54132 1/20 0.54
PMP22 Q01453 1/20 0.54
PDE4B Q07343 1/20 0.54
PDE4C Q08493 1/20 0.54
PDE4D Q08499 1/20 0.54
PDE3B Q13370 1/20 0.54
PDE3A Q14432 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12341730 0.94 ALDH1A1 (0.61) ALDH1A1LMNASRD5A2ATMNPSR1
SCHEMBL6182687 0.91 PLK1 (0.61) ALDH1A1LMNASRD5A2ATMNPSR1
SCHEMBL14958559 0.89 LMNA (0.55) ALDH1A1LMNASRD5A2ATMNPSR1
SCHEMBL14407927 0.89 LMNA (0.55) ALDH1A1LMNASRD5A2ATMNPSR1
SCHEMBL7089334 0.87 CES2 (0.70) ALDH1A1LMNASRD5A2ATMNPSR1
SCHEMBL6427029 0.84 ALDH1A1 (0.73) ALDH1A1LMNASRD5A2ATMNPSR1
SCHEMBL14571023 0.84 ALDH1A1 (0.73) ALDH1A1LMNASRD5A2ATMNPSR1
SCHEMBL31472599 0.84 HAO1 (0.58) ALDH1A1LMNASRD5A2ATMNPSR1
SCHEMBL13814638 0.83 ALDH1A1 (0.48) ALDH1A1LMNASRD5A2ATMNPSR1
SCHEMBL15908231 0.83 ALDH1A1 (0.48) ALDH1A1LMNASRD5A2ATMNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 132 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230340253-A1 RESIN COMPOSITION AND SHAPED ARTICLE KURARAY CO., LTD. (JP) 2023-10-26 US disclosed
EP-4219574-A1 RESIN COMPOSITION AND MOLDED ARTICLE Kuraray Co., Ltd. (JP) 2023-08-02 EP disclosed
US-20230183481-A1 A POLYPHENYLENE SULFIDE/POLYAMIDE COMPOSITION BASF SE (DE) 2023-06-15 US disclosed
US-20230144380-A1 POLYMER HAVING EXCELLENT COMPATIBILITY WITH THERMOPLASTIC RESINS TEIJIN LIMITED (JP) 2023-05-11 US disclosed
WO-2021094858-A1 COMPATIBLIZED HIGH HEAT POLYMER COMPOSITION SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2021-05-20 WO disclosed
US-10941249-B2 Method of preparing polyphenylene sulfide and high-viscosity polyphenylene sulfide prepared using the same LG CHEM, LTD. (KR) 2021-03-09 US disclosed
US-20200181330-A1 METHOD OF PREPARING POLYPHENYLENE SULFIDE AND HIGH-VISCOSITY POLYPHENYLENE SULFIDE PREPARED USING THE SAME LG CHEM, LTD. (KR) 2020-06-11 US disclosed
US-9988521-B2 Polyphenylene sulfide resin composition, production method thereof and reflector TORAY INDUSTRIES, INC. (JP) 2018-06-05 US disclosed
US-9957377-B2 2018-05-01 US disclosed
US-9574065-B2 Thermoplastic resin composition and its molded product TORAY INDUSTRIES, INC. (JP) 2017-02-21 US disclosed
US-20070123627-A1 Polyarylene sulfide thermoplastic resin composition LOTTE ADVANCED MATERIALS CO., LTD. (KR) 2007-05-31 US disclosed
US-20070123627-A1 Polyarylene sulfide thermoplastic resin composition LOTTE ADVANCED MATERIALS CO., LTD. (KR) 2007-05-31 US disclosed
US-7208207-B2 Liner for high pressure gas container and high pressure gas container TOYODA GOSEI CO., LTD. (JP) 2007-04-24 US disclosed
US-7205354-B2 Resin-made mechanical element with excellent heat resistance and dimensional precision for optical disk drive ASAHI KASEI KABUSHIKI KAISHA (JP) 2007-04-17 US disclosed
US-20070066736-A1 Resin composition for reflecting plates OTSUKA CHEMICAL CO., LTD. (JP) 2007-03-22 US disclosed
US-20070021549-A1 Polyphenylene sulfide resin compositions TORAY INDUSTRIES, INC. (JP) 2007-01-25 US disclosed
EP-0891345-B1 NOVEL FURAN DIARYLMETHYLIDENE DERIVATIVES, METHOD FOR THEIR PREPARATION AND THERAPEUTICAL USES THEREOF UNION PHARMA SCIENT APPL (FR) 2001-08-16 EP disclosed
US-6180651-B1 ANTIINFLAMMATORY AGENTS; ANALGESICS BRISTOL-MYERS SQUIBB 2001-01-30 US disclosed
WO-2000014082-A1 DIARYLMETHYLIDENE FURAN DERIVATIVES AS DRUGS WITH ANTI-INFLAMMATORY, ANALGESIC AND CHEMOPREVENTIVE PROPERTIES LABORATORIES UPSA (FR) 2000-03-16 WO disclosed
US-5807873-A Diarylmethylidenefuran derivatives and their uses in therapeutics LABORATORIES UPSA (FR) 1998-09-15 US disclosed