Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 5/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 3/20 | 0.34 |
| ▸ | MMP9 | P14780 | 3/20 | 0.34 |
| ▸ | MMP14 | P50281 | 2/20 | 0.34 |
| ▸ | MMP13 | P45452 | 4/20 | 0.32 |
| ▸ | MMP3 | P08254 | 2/20 | 0.32 |
| ▸ | MMP8 | P22894 | 2/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.30 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | MMP12 | P39900 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7137871 | 0.89 | MMP1 (0.49) | MMP1NR3C1MMP2MMP9MMP14 | |
| SCHEMBL7140254 | 0.83 | MMP1 (0.43) | MMP1MMP2MMP9MMP14MMP13 | |
| SCHEMBL7143794 | 0.71 | MMP1 (0.73) | MMP1MMP2MMP9MMP14MMP13 | |
| SCHEMBL7139241 | 0.68 | MMP1 (0.57) | MMP1MMP2MMP9MMP14MMP13 | |
| SCHEMBL7140995 | 0.66 | MMP1 (0.61) | MMP1MMP2MMP9MMP14MMP13 | |
| SCHEMBL7339033 | 0.64 | AVPR1B (0.34) | MMP1MMP2MMP9MMP13MMP3 | |
| SCHEMBL8443684 | 0.63 | MMP1 (0.51) | MMP1NR3C1MMP2MMP9MMP14 | |
| SCHEMBL7136841 | 0.63 | MMP1 (0.50) | MMP1MMP2MMP9MMP14MMP13 | |
| SCHEMBL6862333 | 0.63 | MMP1 (0.50) | MMP1NR3C1MMP2MMP9MMP14 | |
| SCHEMBL7330071 | 0.63 | MMP1 (0.59) | MMP1MMP2MMP9MMP14MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041072-A1 | Dioxocyclopentyl hydroxamic acids | Pfizer Products Inc. (US) | 2000-10-04 | — | — | EP | disclosed |