Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1B | P47901 | 7/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 6/20 | 0.32 |
| ▸ | MMP13 | P45452 | 5/20 | 0.32 |
| ▸ | RORC | P51449 | 3/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7137871 | 0.65 | MMP1 (0.49) | MMP1MMP13MMP2MMP3MMP9 | |
| Hydroxyamine SCHEMBL7339030 | 0.64 | MMP1 (0.40) | MAPTNPSR1MMP1MMP13MMP2 | |
| SCHEMBL7140254 | 0.59 | MMP1 (0.43) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL7161720 | 0.56 | MMP1 (0.35) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL1133869 | 0.54 | MMP8 (0.65) | LMNAMMP1MMP13MMP2MMP9 | |
| SCHEMBL27415618 | 0.53 | MMP1 (0.50) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL14842844 | 0.53 | MEN1 (0.76) | MAPTLMNANPSR1MEN1KMT2A | |
| SCHEMBL7430258 | 0.53 | MMP2 (0.52) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL27543888 | 0.52 | BCL2L1 (0.51) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL6869740 | 0.52 | MMP1 (0.77) | MMP1MMP13MMP2MMP3MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041072-A1 | Dioxocyclopentyl hydroxamic acids | Pfizer Products Inc. (US) | 2000-10-04 | — | — | EP | disclosed |