Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 1/20 | 0.34 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | TYMS | P04818 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 2/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.31 |
| ▸ | TUBB | P07437 | 1/20 | 0.31 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.31 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.31 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.31 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.31 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7339135 | 0.73 | PLAU (0.56) | MAPTPLAUF2PRSS1TP53 | |
| SCHEMBL7337592 | 0.69 | PLAU (0.60) | PLAUF2PRSS1 | |
| SCHEMBL28080814 | 0.62 | HTT (0.54) | MAPTKMT2AALDH1A1TSHRHSD17B10 | |
| SCHEMBL7721608 | 0.62 | MRGPRX1 (0.55) | MAPTALDH1A1TSHRHSD17B10NPC1 | |
| SCHEMBL7279705 | 0.60 | MAPT (0.55) | MAPTKMT2AALDH1A1HSD17B10TUBB4A | |
| SCHEMBL5188238 | 0.60 | TYMS (0.40) | TOP2ATOP2BMAPTTYMSKMT2A | |
| 1,2-Dimethoxybenzene SCHEMBL28862840 | 0.60 | CA1 (0.62) | KMT2AALDH1A1TSHRTP53 | |
| SCHEMBL10701583 | 0.59 | MMP2 (0.54) | KMT2AHSD17B10TUBB4ATUBBTUBA3C | |
| SCHEMBL10700610 | 0.59 | L3MBTL1 (0.45) | MAPTKMT2AALDH1A1TUBB4ATUBB | |
| SCHEMBL6191884 | 0.59 | ALDH1A1 (0.47) | MAPTKMT2AALDH1A1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6284796-B1 | NAPHTHAMIDINE COMPOUNDS | ABBOTT LABORATORIES | 2001-09-04 | — | — | US | disclosed |