Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | P2RY6 | Q15077 | 14/20 | 0.37 |
| ▸ | P2RY2 | P41231 | 12/20 | 0.37 |
| ▸ | P2RY4 | P51582 | 11/20 | 0.37 |
| ▸ | NT5E | P21589 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL733570 | 0.88 | POLB (0.39) | POLBP2RY6P2RY2P2RY4ABL1 | |
| SCHEMBL733590 | 0.88 | P2RY6 (0.36) | POLBP2RY6P2RY2P2RY4NT5E | |
| SCHEMBL735248 | 0.79 | ADORA3 (0.43) | — | |
| SCHEMBL2112368 | 0.73 | POLB (0.42) | POLBP2RY6P2RY2P2RY4NT5E | |
| SCHEMBL2112367 | 0.71 | POLB (0.40) | POLBP2RY6NT5EABL1RIN1 | |
| SCHEMBL8607542 | 0.71 | POLB (0.49) | POLBP2RY6NT5EABL1RIN1 | |
| SCHEMBL2113460 | 0.71 | POLB (0.41) | POLBP2RY6P2RY2P2RY4NT5E | |
| SCHEMBL618137 | 0.70 | POLB (0.39) | POLBP2RY6P2RY2P2RY4NT5E | |
| SCHEMBL2270354 | 0.70 | POLB (0.38) | POLBP2RY6P2RY2P2RY4NT5E | |
| SCHEMBL332974 | 0.70 | POLB (0.49) | POLBP2RY6NT5EABL1RIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138330-B2 | Solid phase synthesis via deblocking immobilized nucleoside, then coupling acyl protected nucleoside phosphoramidite | SIGMA-ALDRICH CO. LLC (US) | 2012-03-20 | — | — | US | disclosed |