Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.37 |
| ▸ | TYMP | P19971 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL736838 | 0.89 | PRMT5 (0.38) | ADORA3PRMT5WDR77ADORA2AADORA2B | |
| SCHEMBL735341 | 0.89 | ADORA3 (0.38) | ADORA3PRMT5WDR77TYMP | |
| SCHEMBL733396 | 0.84 | ADORA3 (0.41) | ADORA3PRMT5WDR77ADORA2AADORA2B | |
| SCHEMBL733926 | 0.79 | POLB (0.38) | — | |
| SCHEMBL5859661 | 0.76 | P2RX3 (0.43) | — | |
| SCHEMBL733412 | 0.74 | RNMT (0.30) | — | |
| SCHEMBL735543 | 0.74 | TYMP (0.64) | ADORA3PRMT5WDR77TYMP | |
| SCHEMBL888001 | 0.73 | ADORA3 (0.45) | ADORA3ADORA2AADORA2B | |
| SCHEMBL888000 | 0.72 | ADORA3 (0.43) | ADORA3ADORA2A | |
| SCHEMBL2112347 | 0.71 | ADORA3 (0.47) | ADORA3ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138330-B2 | Solid phase synthesis via deblocking immobilized nucleoside, then coupling acyl protected nucleoside phosphoramidite | SIGMA-ALDRICH CO. LLC (US) | 2012-03-20 | — | — | US | disclosed |