Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | P2RY6 | Q15077 | 3/20 | 0.32 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.32 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL733926 | 0.88 | POLB (0.38) | POLBP2RY6P2RY2P2RY4ABL1 | |
| SCHEMBL736838 | 0.80 | PRMT5 (0.38) | — | |
| SCHEMBL733590 | 0.77 | P2RY6 (0.36) | POLBP2RY6P2RY2P2RY4ABL1 | |
| SCHEMBL734857 | 0.75 | POLB (0.43) | POLBP2RY6P2RY2P2RY4ABL1 | |
| SCHEMBL735248 | 0.68 | ADORA3 (0.43) | — | |
| SCHEMBL25633109 | 0.67 | POLB (0.59) | POLBP2RY6P2RY2P2RY4ABL1 | |
| SCHEMBL25633203 | 0.67 | POLB (0.59) | POLBP2RY6P2RY2P2RY4ABL1 | |
| SCHEMBL8003052 | 0.66 | POLB (0.76) | POLBP2RY6P2RY2P2RY4ABL1 | |
| SCHEMBL9702839 | 0.66 | POLB (0.76) | POLBP2RY6P2RY2P2RY4ABL1 | |
| SCHEMBL9242816 | 0.66 | POLB (0.65) | POLBP2RY6P2RY2P2RY4ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138330-B2 | Solid phase synthesis via deblocking immobilized nucleoside, then coupling acyl protected nucleoside phosphoramidite | SIGMA-ALDRICH CO. LLC (US) | 2012-03-20 | — | — | US | disclosed |