Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | MMP12 | P39900 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7345264 | 0.89 | SMN1; SMN2 (0.59) | ALDH1A1SMN1; SMN2LMNAMAPTKMT2A | |
| SCHEMBL2771639 | 0.89 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1MAPK1SMN1; SMN2LMNA | |
| SCHEMBL7336549 | 0.85 | SMN1; SMN2 (0.61) | ALDH1A1SMN1; SMN2LMNAMAPTKMT2A | |
| SCHEMBL2353279 | 0.83 | POLB (0.58) | ALDH1A1L3MBTL1MAPK1SMN1; SMN2LMNA | |
| SCHEMBL8815917 | 0.81 | SLC6A2 (0.61) | ALDH1A1SMN1; SMN2LMNAKMT2ANPC1 | |
| Ammonia Solution, Strong SCHEMBL27681752 | 0.81 | ALDH1A1 (0.66) | ALDH1A1L3MBTL1MAPK1SMN1; SMN2LMNA | |
| SCHEMBL7346082 | 0.81 | SMN1; SMN2 (0.54) | ALDH1A1SMN1; SMN2LMNAMAPTKMT2A | |
| SCHEMBL7343260 | 0.81 | MAPT (0.51) | ALDH1A1L3MBTL1SMN1; SMN2LMNAMAPT | |
| SCHEMBL17653809 | 0.80 | LMNA (0.62) | SMN1; SMN2LMNAMAPTKMT2APOLB | |
| SCHEMBL344303 | 0.80 | NPC1 (0.59) | ALDH1A1L3MBTL1MAPK1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5622984-A | INHIBITORS OF PHOSPHOLIPASE, VARIOUS PROTEASES | ONO PHARMACEUTICAL COMPANY, LIMITED (JP) | 1997-04-22 | — | — | US | disclosed |
| US-5614555-A | Amidinophenol derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1997-03-25 | — | — | US | disclosed |
| EP-0588655-B1 | Amidinophenol derivatives | ONO PHARMACEUTICAL CO (JP) | 1996-12-04 | — | — | EP | disclosed |
| US-5432178-A | Substituted benzoic acid esters; use to prevent or treat inflammatory diseases, allergic diseases, disseminated intravascular coagulation, pancreatitis or multiple organ failure | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-07-11 | — | — | US | disclosed |
| EP-0588655-A1 | Amidinophenol derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-03-23 | — | — | EP | disclosed |