Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL91231 | 0.75 | ADRA2B (0.52) | KMT2AMEN1ALDH1A1RIPK1SIGMAR1 | |
| SCHEMBL5431000 | 0.73 | IDO1 (0.50) | KMT2AMEN1ALDH1A1RIPK1SMN1; SMN2 | |
| SCHEMBL4154636 | 0.73 | IDO1 (0.50) | KMT2AMEN1ALDH1A1RIPK1SMN1; SMN2 | |
| SCHEMBL10703980 | 0.70 | RAB9A (0.50) | KMT2AMEN1ALDH1A1RIPK1MAPT | |
| SCHEMBL10949413 | 0.70 | SLC6A2 (0.48) | KMT2AMEN1ALDH1A1RIPK1SMN1; SMN2 | |
| SCHEMBL5479640 | 0.70 | SIGMAR1 (0.47) | KMT2AMEN1ALDH1A1RIPK1SIGMAR1 | |
| SCHEMBL19047067 | 0.70 | SIGMAR1 (0.47) | KMT2AMEN1ALDH1A1RIPK1SIGMAR1 | |
| SCHEMBL5485988 | 0.69 | CYP3A4 (0.48) | KMT2AMEN1ALDH1A1RIPK1SIGMAR1 | |
| SCHEMBL125129 | 0.68 | CYP3A4 (0.52) | KMT2AMEN1RIPK1SIGMAR1MAPT | |
| SCHEMBL9482260 | 0.68 | IDO1 (0.61) | KMT2AMEN1ALDH1A1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200188459-A1 | PROCESS FOR PREPARING METABOLIZED CONDITIONED GROWTH MEDIA | ALLERGAN INC (US) | 2020-06-18 | — | — | US | disclosed |
| EP-3527214-A1 | METABOLIZED CONDITIONED GROWTH MEDIUM AND METHODS OF USE | ALLERGAN, INC. (US) | 2019-08-21 | — | — | EP | disclosed |
| US-20190175672-A1 | PROCESS FOR PREPARING METABOLIZED CONDITIONED GROWTH MEDIA | ALLERGAN INC (US) | 2019-06-13 | — | — | US | disclosed |
| EP-2637641-B1 | METABOLIZED CONDITIONED GROWTH MEDIUM AND METHODS OF USE | ALLERGAN INC (US) | 2019-02-20 | — | — | EP | disclosed |
| US-10206961-B2 | Process for preparing metabolized conditioned growth media | ALLERGAN, INC. (US) | 2019-02-19 | — | — | US | disclosed |
| EP-2799080-B1 | Metabolized conditioned growth medium and methods of use | ALLERGAN INC (US) | 2019-01-09 | — | — | EP | disclosed |
| US-20170055561-A1 | CONDITIONED CELL CULTURE MEDIUM COMPOSITIONS AND METHODS OF USE | ALLERGAN, INC. | 2017-03-02 | — | — | US | disclosed |
| US-9458486-B2 | Conditioned cell culture medium compositions and methods of use | ALLERGEN, INC. (US) | 2016-10-04 | — | — | US | disclosed |
| US-9408881-B2 | Topical composition | ALLERGAN, INC. (US) | 2016-08-09 | — | — | US | disclosed |
| EP-2799077-A1 | Metabolized conditioned growth medium and methods of use | ALLERGAN, INC. (US) | 2014-11-05 | — | — | EP | disclosed |
| US-8138147-B2 | Conditioned cell culture medium compositions and methods of use | SKINMEDICA, INC. (US) | 2012-03-20 | — | — | US | disclosed |
| US-20090123503-A1 | Conditioned Cell Culture Medium Compositions and Methods of Use | SKINMEDICA. INC. (US) | 2009-05-14 | — | — | US | disclosed |
| US-20070077232-A1 | Conditioned cell culture medium compositions and methods of use | SKINMEDICA, INC. (US) | 2007-04-05 | — | — | US | disclosed |
| US-7118746-B1 | Conditioned cell culture medium compositions and methods of use | SKINMEDICA, INC. (US) | 2006-10-10 | — | — | US | disclosed |
| US-20060165667-A1 | Novel methods, compositions and devices for inducing neovascularization | CASE WESTERN RESERVE UNIVERSITY (US) | 2006-07-27 | — | — | US | disclosed |
| WO-2006060779-A2 | NOVEL METHODS, COMPOSITIONS AND DEVICES FOR INDUCING NEOVASCULARIZATION | CASE WESTERN RESERVE UNIVERSITY (US) | 2006-06-08 | — | — | WO | disclosed |
| EP-1178812-B1 | METHODS OF MAKING CONDITIONED CELL CULTURE MEDIUM COMPOSITIONS | SKINMEDICA INC (US) | 2005-12-07 | — | — | EP | disclosed |
| US-6372494-B1 | CULTURING FIBROBLAST CELLS IN THREE-DIMENSIONS IN A CELL CULTURE MEDIUM; REMOVING CONDITIONED MEDIUM FROM THE CULTURED CELLS; COMBINING CONDITIONED MEDIUM WITH A PHARMACEUTICALLY ACCEPTABLE CARRIER | ADVANCED TISSUE SCIENCES, INC. | 2002-04-16 | — | — | US | disclosed |
| EP-1178812-A2 | CONDITIONED CELL CULTURE MEDIUM COMPOSITIONS AND METHODS OF USE | ADVANCED TISSUE SCIENCES, INC. (US) | 2002-02-13 | — | — | EP | disclosed |
| WO-2000069449-A2 | CONDITIONED CELL CULTURE MEDIUM COMPOSITIONS AND METHODS OF USE | ADVANCED TISSUE SCIENCES, INC. (US) | 2000-11-23 | — | — | WO | disclosed |