Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL1RN | P18510 | 1/20 | 0.48 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.48 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.48 |
| ▸ | BDKRB2 | P30411 | 3/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | YAP1 | P46937 | 3/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.46 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.46 |
| ▸ | MME | P08473 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 1/20 | 0.45 |
| ▸ | CPA1 | P15085 | 1/20 | 0.45 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7337924 | 0.85 | YAP1 (0.56) | IL1RNERAP2ERAP1MMP9MMP8 | |
| SCHEMBL7342359 | 0.84 | YAP1 (0.55) | IL1RNERAP2ERAP1MMP9MMP8 | |
| SCHEMBL7338585 | 0.83 | UTS2R (0.57) | — | |
| SCHEMBL7345278 | 0.83 | UTS2R (0.57) | — | |
| SCHEMBL7339723 | 0.83 | MMP9 (0.44) | BDKRB2MMP9MMP8YAP1MME | |
| SCHEMBL7338808 | 0.83 | YAP1 (0.45) | IL1RNERAP2ERAP1MMP9MMP8 | |
| SCHEMBL7342587 | 0.82 | YAP1 (0.51) | IL1RNERAP2ERAP1MMP9MMP8 | |
| SCHEMBL7348165 | 0.81 | YAP1 (0.47) | IL1RNERAP2ERAP1MMP9MMP8 | |
| SCHEMBL7337028 | 0.81 | PSMB1 (0.58) | IL1RNERAP2ERAP1MMP9MMP8 | |
| SCHEMBL7337109 | 0.80 | YAP1 (0.49) | IL1RNERAP2ERAP1YAP1MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | claimed |
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | disclosed |