Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.40 |
| ▸ | CTSS | P25774 | 6/20 | 0.39 |
| ▸ | CTSK | P43235 | 5/20 | 0.39 |
| ▸ | CTSB | P07858 | 4/20 | 0.39 |
| ▸ | GHSR | Q92847 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 6/20 | 0.37 |
| ▸ | MME | P08473 | 1/20 | 0.36 |
| ▸ | ECE1 | P42892 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CTSV | O60911 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7340088 | 0.85 | GHSR (0.40) | NAALAD2TRPV1CTSSCTSKCTSB | |
| SCHEMBL7340108 | 0.84 | NAALAD2 (0.43) | NAALAD2TRPV1CTSSCTSKCTSB | |
| SCHEMBL8922575 | 0.79 | GHSR (0.48) | NAALAD2TRPV1GHSRMMEECE1 | |
| SCHEMBL8922585 | 0.79 | GHSR (0.48) | NAALAD2TRPV1GHSRMMEECE1 | |
| SCHEMBL7340127 | 0.79 | NAALAD2 (0.41) | NAALAD2TRPV1CTSSCTSKCTSB | |
| SCHEMBL7342977 | 0.76 | L3MBTL1 (0.40) | CTSSCTSLMMEECE1L3MBTL1 | |
| SCHEMBL7309933 | 0.74 | MMEL1 (0.59) | MMEL3MBTL1 | |
| SCHEMBL7318069 | 0.74 | MMEL1 (0.59) | MMEL3MBTL1 | |
| SCHEMBL7354164 | 0.71 | L3MBTL1 (0.46) | CTSSCTSLL3MBTL1 | |
| SCHEMBL8922494 | 0.70 | GHSR (0.46) | NAALAD2GHSRMMEECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0592367-A2 | Phosphono/biaryl substituted dipeptide derivatives | CIBA-GEIGY AG (CH) | 1994-04-13 | — | — | EP | disclosed |