Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 3/20 | 0.39 |
| ▸ | ECE1 | P42892 | 3/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.38 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7342429 | 0.89 | MME (0.49) | L3MBTL1MMEECE1AGTR2MMEL1 | |
| SCHEMBL7342991 | 0.83 | MME (0.39) | MMEECE1AGTR2MMEL1 | |
| SCHEMBL7309933 | 0.80 | MMEL1 (0.59) | L3MBTL1MMEMMEL1 | |
| SCHEMBL7318069 | 0.80 | MMEL1 (0.59) | L3MBTL1MMEMMEL1 | |
| SCHEMBL8921710 | 0.76 | ECE1 (0.49) | MMEECE1AGTR2MMEL1 | |
| SCHEMBL8923646 | 0.76 | ECE1 (0.49) | MMEECE1AGTR2MMEL1 | |
| SCHEMBL7354164 | 0.76 | L3MBTL1 (0.46) | L3MBTL1MMEL1CTSLCTSS | |
| SCHEMBL7340085 | 0.76 | NAALAD2 (0.42) | L3MBTL1MMEECE1CTSLCTSS | |
| SCHEMBL7343009 | 0.76 | HDAC3 (0.39) | MMEECE1AGTR2MMEL1 | |
| SCHEMBL7319489 | 0.76 | CTSS (0.49) | L3MBTL1MMEL1CTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0592367-A2 | Phosphono/biaryl substituted dipeptide derivatives | CIBA-GEIGY AG (CH) | 1994-04-13 | — | — | EP | disclosed |
| US-5294632-A | Diuretics and vasorelaxants | CIBA-GEIGY CORPORATION (US) | 1994-03-15 | — | — | US | disclosed |