Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.35 |
| ▸ | F10 | P00742 | 2/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7340563 | 0.89 | RXFP1 (0.35) | HTTL3MBTL1SMN1; SMN2GAARXFP1 | |
| SCHEMBL7343615 | 0.81 | SMN1; SMN2 (0.38) | HTTL3MBTL1SMN1; SMN2GAAITGB3 | |
| SCHEMBL7340566 | 0.78 | PTPRC (0.33) | SMN1; SMN2ITGB3RXFP1KMT2AMEN1 | |
| SCHEMBL7348070 | 0.77 | HTT (0.38) | HTTL3MBTL1SMN1; SMN2GAAITGB3 | |
| SCHEMBL7345087 | 0.76 | SMN1; SMN2 (0.38) | HTTL3MBTL1SMN1; SMN2GAAITGB3 | |
| SCHEMBL6773153 | 0.75 | ITGB3 (0.55) | HTTL3MBTL1SMN1; SMN2GAAITGB3 | |
| SCHEMBL7340322 | 0.74 | EPHX2 (0.37) | HTTL3MBTL1SMN1; SMN2GAAITGB3 | |
| SCHEMBL7347196 | 0.73 | HTT (0.37) | HTTL3MBTL1SMN1; SMN2GAAITGB3 | |
| SCHEMBL6366986 | 0.73 | PLA2G10 (0.47) | HTTL3MBTL1SMN1; SMN2ITGB3ITGA2B | |
| SCHEMBL27502754 | 0.72 | ITGB3 (0.47) | HTTL3MBTL1SMN1; SMN2GAAITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850221-A1 | META-GUANIDINE, UREA, THIOUREA OR AZACYCLIC AMINO BENZOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1998-07-01 | — | — | EP | claimed |
| WO-1997008145-A1 | META-GUANIDINE, UREA, THIOUREA OR AZACYCLIC AMINO BENZOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1997-03-06 | — | — | WO | claimed |