Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 5/20 | 0.34 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.34 |
| ▸ | PTPRC | P08575 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7340450 | 0.89 | HTT (0.37) | RXFP1ALDH1A1GAAMAPTMEN1 | |
| SCHEMBL7340566 | 0.88 | PTPRC (0.33) | RXFP1ALDH1A1POLBANO1PTPRC | |
| SCHEMBL7343615 | 0.71 | SMN1; SMN2 (0.38) | RXFP1ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL7453096 | 0.71 | LMNA (0.48) | ALDH1A1GAAMAPTMEN1KMT2A | |
| SCHEMBL7343247 | 0.70 | EPHX2 (0.36) | RXFP1F2ALDH1A1GAAMAPT | |
| SCHEMBL8524728 | 0.69 | PRMT5 (0.42) | F2TMPRSS6PTPRCPRMT5WDR77 | |
| SCHEMBL6778844 | 0.69 | PTPRC (0.37) | F2TMPRSS6ALDH1A1POLBPTPRC | |
| SCHEMBL7339143 | 0.68 | RXFP1 (0.48) | RXFP1ALDH1A1POLBGAAMEN1 | |
| SCHEMBL26049628 | 0.68 | NPSR1 (0.46) | RXFP1ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL7348070 | 0.68 | HTT (0.38) | RXFP1GAAMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850221-A1 | META-GUANIDINE, UREA, THIOUREA OR AZACYCLIC AMINO BENZOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1998-07-01 | — | — | EP | claimed |
| WO-1997008145-A1 | META-GUANIDINE, UREA, THIOUREA OR AZACYCLIC AMINO BENZOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1997-03-06 | — | — | WO | claimed |