Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.31 |
| ▸ | ITGAV | P06756 | 1/20 | 0.31 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7340563 | 0.88 | RXFP1 (0.35) | PTPRCSMN1; SMN2MEN1KMT2ARXFP1 | |
| SCHEMBL7340450 | 0.78 | HTT (0.37) | SMN1; SMN2MEN1KMT2ARXFP1ITGB3 | |
| SCHEMBL7343256 | 0.71 | KMT2A (0.37) | SMN1; SMN2MEN1KMT2AITGB3ITGAV | |
| SCHEMBL7345104 | 0.69 | ITGB3 (0.34) | SMN1; SMN2MEN1KMT2AITGB3ITGAV | |
| SCHEMBL7344227 | 0.68 | HTT (0.40) | SMN1; SMN2MEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL7379459 | 0.67 | PTGS2 (0.39) | MEN1KMT2AITGB3ITGAV | |
| SCHEMBL7414335 | 0.67 | NR1H4 (0.42) | SMN1; SMN2MEN1KMT2AITGB3ITGAV | |
| SCHEMBL6778846 | 0.67 | KMT2A (0.36) | PTPRCSMN1; SMN2MEN1KMT2AITGB3 | |
| SCHEMBL6778203 | 0.67 | CTSS (0.47) | SMN1; SMN2ITGB3ITGAVMAPK1ALDH1A1 | |
| SCHEMBL7835688 | 0.66 | SMN1; SMN2 (0.36) | SMN1; SMN2ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850221-A1 | META-GUANIDINE, UREA, THIOUREA OR AZACYCLIC AMINO BENZOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1998-07-01 | — | — | EP | claimed |
| WO-1997008145-A1 | META-GUANIDINE, UREA, THIOUREA OR AZACYCLIC AMINO BENZOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1997-03-06 | — | — | WO | claimed |