Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | EED | O75530 | 1/20 | 0.41 |
| ▸ | CAPN1 | P07384 | 3/20 | 0.41 |
| ▸ | CTSB | P07858 | 3/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 3/20 | 0.40 |
| ▸ | NOS3 | P29474 | 2/20 | 0.40 |
| ▸ | NOS1 | P29475 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7343130 | 0.90 | CTSL (0.42) | CACNA1BCTSLMMP1FCER2 | |
| SCHEMBL7348064 | 0.90 | CTSL (0.42) | CACNA1BCTSLMMP1FCER2 | |
| SCHEMBL7337043 | 0.87 | ACACB (0.43) | CACNA1BCTSL | |
| SCHEMBL7344643 | 0.85 | FFAR1 (0.40) | PPARGCACNA1BCTSLMMP1 | |
| SCHEMBL7341159 | 0.85 | PTPN1 (0.44) | CAPN1CTSBCACNA1BCTSLCTSS | |
| SCHEMBL7338154 | 0.85 | PPARG (0.51) | PPARG | |
| SCHEMBL7339993 | 0.84 | CACNA1B (0.35) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL7347656 | 0.84 | CACNA1B (0.36) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL7348620 | 0.84 | NOS2 (0.37) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL7338183 | 0.81 | KMT2A (0.41) | CAPN1CTSBCACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | claimed |
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | disclosed |