Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | F7 | P08709 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.37 |
| ▸ | ITGAV | P06756 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7348064 | 0.89 | CTSL (0.42) | CTSLPSMB5CACNA1BMMP1MMP2 | |
| SCHEMBL7343130 | 0.89 | CTSL (0.42) | CTSLCACNA1BMMP1MMP2MMP3 | |
| SCHEMBL7340724 | 0.85 | PPARG (0.43) | CTSLPPARGCACNA1BMMP1 | |
| SCHEMBL7337043 | 0.85 | ACACB (0.43) | CTSLCACNA1BMMP2 | |
| SCHEMBL7341159 | 0.84 | PTPN1 (0.44) | CTSLF7PSMB5CACNA1BMMP1 | |
| SCHEMBL7338154 | 0.84 | PPARG (0.51) | PPARGITGB3ITGA2BSMN1; SMN2NPC1 | |
| SCHEMBL7347656 | 0.81 | CACNA1B (0.36) | CTSLITGB3ITGB1ITGAVITGA2B | |
| SCHEMBL6840142 | 0.79 | FCER2 (0.49) | PPARGMMP1MMP2MMP3NPC1 | |
| SCHEMBL7338183 | 0.79 | KMT2A (0.41) | PSMB5CACNA1BSMN1; SMN2MEN1KMT2A | |
| SCHEMBL7338601 | 0.79 | ACACB (0.36) | CTSLCACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | claimed |
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | disclosed |