Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | F11 | P03951 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | ALPG | P10696 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11047561 | 0.80 | KDR (0.61) | KDRHPGDPARP1HRH4HRH3 | |
| SCHEMBL27544887 | 0.80 | ACHE (0.61) | ALDH1A1MAPTHSD17B10KDM4EHPGD | |
| Hydrochloric Acid SCHEMBL11041364 | 0.79 | KDR (0.60) | KDRHPGDPARP1HRH4HRH3 | |
| Hydrochloric Acid SCHEMBL27470973 | 0.79 | ACHE (0.60) | ALDH1A1MAPTHSD17B10KDM4EHPGD | |
| SCHEMBL10838243 | 0.78 | MAPT (0.56) | ALDH1A1MAPTHSD17B10KDM4EHPGD | |
| SCHEMBL7341203 | 0.77 | MGLL (0.51) | ALDH1A1KDM4EACHECA12CA9 | |
| Hydrochloric Acid SCHEMBL7342602 | 0.76 | MGLL (0.49) | ALDH1A1KDM4EACHECA12CA9 | |
| SCHEMBL7348389 | 0.75 | ALDH1A1 (0.54) | ALDH1A1MAPTKDM4EHPGDCA12 | |
| SCHEMBL7350662 | 0.75 | CA12 (0.49) | ALDH1A1MAPTKDM4EHPGDCA12 | |
| SCHEMBL7269188 | 0.73 | GRIN2B (0.47) | ALDH1A1MAPTHSD17B10KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4514401-A | CARDIOTONICS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1985-04-30 | — | — | US | disclosed |