Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.44 |
| ▸ | OXTR | P30559 | 2/20 | 0.44 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.44 |
| ▸ | MTTP | P55157 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7334184 | 0.93 | TP53 (0.47) | CHRNB2CHRNB4CHRNA3CHRNA4AVPR2 | |
| SCHEMBL7334422 | 0.89 | TP53 (0.41) | — | |
| SCHEMBL7342685 | 0.88 | TP53 (0.40) | — | |
| SCHEMBL7343236 | 0.88 | AVPR2 (0.45) | AVPR2AVPR1A | |
| SCHEMBL7345166 | 0.88 | TP53 (0.44) | — | |
| SCHEMBL7345315 | 0.87 | TP53 (0.40) | — | |
| SCHEMBL7345024 | 0.87 | AVPR2 (0.45) | AVPR2OXTRAVPR1A | |
| SCHEMBL7335374 | 0.86 | CHRNB2 (0.43) | CHRNB2CHRNB4CHRNA3CHRNA4AVPR2 | |
| SCHEMBL7335173 | 0.86 | LMNA (0.40) | — | |
| SCHEMBL7334302 | 0.86 | LMNA (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996022282-A1 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | AMERICAN CYANAMID COMPANY (US) | 1996-07-25 | — | — | WO | claimed |
| WO-1996022282-A1 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | AMERICAN CYANAMID COMPANY (US) | 1996-07-25 | — | — | WO | disclosed |