Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | DRD3 | P35462 | 2/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6566519 | 0.81 | MAPK1 (0.69) | MAPK1ALDH1A1POLBTSHRSMN1; SMN2 | |
| SCHEMBL8322902 | 0.78 | RXRA (0.61) | ALDH1A1SMN1; SMN2RAB9AGAA | |
| SCHEMBL8322900 | 0.78 | RXRA (0.61) | ALDH1A1SMN1; SMN2RAB9AGAA | |
| SCHEMBL9798906 | 0.77 | MAPK1 (0.69) | MAPK1ALDH1A1POLBTSHRSMN1; SMN2 | |
| SCHEMBL7383650 | 0.77 | TSHR (0.69) | ALDH1A1TSHRKMT2ASMN1; SMN2RAB9A | |
| SCHEMBL14121833 | 0.74 | TSHR (0.66) | ALDH1A1TSHRKMT2ASMN1; SMN2RAB9A | |
| SCHEMBL30231919 | 0.73 | RAB9A (0.60) | ALDH1A1POLBTSHRKMT2ASMN1; SMN2 | |
| SCHEMBL7345208 | 0.73 | RAB9A (0.61) | ALDH1A1TSHRKMT2ASMN1; SMN2RAB9A | |
| SCHEMBL7339688 | 0.73 | RAB9A (0.60) | MAPK1ALDH1A1TSHRKMT2ASMN1; SMN2 | |
| SCHEMBL4175190 | 0.72 | NR1H3 (0.49) | ALDH1A1NR1H3KMT2AL3MBTL1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832061-B1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| US-6054457-A | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-25 | — | — | US | disclosed |
| WO-1996041795-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-27 | — | — | WO | disclosed |