Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | BACE1 | P56817 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6566519 | 0.83 | MAPK1 (0.69) | MAPK1ALDH1A1POLBTSHRGAA | |
| SCHEMBL15693964 | 0.82 | ALDH1A1 (0.55) | MAPK1ALDH1A1TSHRL3MBTL1MAPT | |
| SCHEMBL16718938 | 0.82 | RAB9A (0.65) | MAPK1POLBGAAL3MBTL1MAPT | |
| SCHEMBL616023 | 0.81 | RAB9A (0.61) | MAPK1ALDH1A1POLBTSHRGAA | |
| SCHEMBL25039756 | 0.81 | ALDH1A1 (0.54) | MAPK1ALDH1A1POLBTSHRL3MBTL1 | |
| SCHEMBL29729331 | 0.81 | ALDH1A1 (0.54) | MAPK1ALDH1A1POLBTSHRL3MBTL1 | |
| SCHEMBL7383650 | 0.81 | TSHR (0.69) | ALDH1A1TSHRL3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL2149738 | 0.81 | MAPT (0.66) | MAPK1ALDH1A1TSHRMAPTHSP90AA1 | |
| SCHEMBL5767014 | 0.79 | MAPT (0.64) | TSHRMAPTHSP90AA1HTTNPSR1 | |
| SCHEMBL1506144 | 0.79 | ALDH1A1 (0.53) | MAPK1ALDH1A1POLBTSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5061720-A | ANTIINFLAMMATORY AGENTS FOR TOPICAL APPLICATION TO SKIN | A. H. ROBINS COMPANY, INC. (US) | 1991-10-29 | — | — | US | disclosed |