SCHEMBL734096

SCHEMBL734096

Brc1ccccc1-c1cc(Br)c(-c2ccccc2Br)cc1Br

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.55
MAPK1 P28482 3/20 0.55
MAOB P27338 4/20 0.43
MAOA P21397 3/20 0.43
DCUN1D1 Q96GG9 2/20 0.41
PBRM1 Q86U86 1/20 0.40
IDO1 P14902 1/20 0.40
LMNA P02545 1/20 0.40
MAPK14 Q16539 1/20 0.39
MAPT P10636 3/20 0.39
HPGD P15428 2/20 0.39
KDM4E B2RXH2 1/20 0.39
GAA P10253 1/20 0.39
MPI P34949 1/20 0.39
APOBEC3G Q9HC16 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
HSD17B10 Q99714 1/20 0.39
HKDC1 Q2TB90 1/20 0.39
GRM2 Q14416 1/20 0.38
TAAR1 Q96RJ0 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16193372 1.00 ALDH1A1 (0.55) ALDH1A1MAPK1MAOBMAOADCUN1D1
SCHEMBL2167441 0.92 ALDH1A1 (0.52) ALDH1A1MAPK1MAOBMAOADCUN1D1
SCHEMBL12403143 0.88 MAOB (0.46) ALDH1A1MAPK1MAOBMAOADCUN1D1
SCHEMBL31295703 0.87 ALDH1A1 (0.67) ALDH1A1MAPK1MAOBMAOADCUN1D1
SCHEMBL358976 0.87 ALDH1A1 (0.67) ALDH1A1MAPK1MAOBMAOADCUN1D1
SCHEMBL19571031 0.87 MAPK1 (0.48) ALDH1A1MAPK1MAOBMAOADCUN1D1
SCHEMBL29052309 0.85 MAOB (0.47) ALDH1A1MAPK1MAOBMAOADCUN1D1
SCHEMBL7519287 0.84 ALDH1A1 (0.63) ALDH1A1MAPK1MAOBMAOADCUN1D1
SCHEMBL31465796 0.84 ALDH1A1 (0.63) ALDH1A1MAPK1MAOBMAOADCUN1D1
Bromide SCHEMBL6343983 0.81 ALDH1A1 (0.60) ALDH1A1MAPK1MAOBMAOADCUN1D1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10370484-B2 Polymer compound and light emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2019-08-06 US disclosed
EP-2067782-B2 HETEROACENE DERIVATIVE, TETRAHALOTERPHENYL DERIVATIVE, AND THEIR PRODUCTION METHODS TOSOH CORP (JP) 2018-06-27 EP disclosed
US-20170137566-A1 POLYMER COMPOUND AND LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-05-18 US disclosed
US-20170137566-A1 POLYMER COMPOUND AND LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-05-18 US disclosed
EP-3165550-A1 POLYMERIC COMPOUND AND LIGHT-EMITTING ELEMENT USING SAME Sumitomo Chemical Company Limited (JP) 2017-05-10 EP disclosed
EP-1867623-B1 TERPHENYLENE DERIVATIVES, TETRAHALOTERPHENYL DERIVATIVES AND PROCESSES FOR THE PRODUCTION OF BOTH TOSOH CORP (JP) 2017-05-10 EP disclosed
EP-1867623-B1 TERPHENYLENE DERIVATIVES, TETRAHALOTERPHENYL DERIVATIVES AND PROCESSES FOR THE PRODUCTION OF BOTH TOSOH CORP (JP) 2017-05-10 EP disclosed
EP-2067782-B1 HETEROACENE DERIVATIVE, TETRAHALOTERPHENYL DERIVATIVE, AND THEIR PRODUCTION METHODS TOSOH CORP (JP) 2014-08-13 EP disclosed
EP-2067782-B1 HETEROACENE DERIVATIVE, TETRAHALOTERPHENYL DERIVATIVE, AND THEIR PRODUCTION METHODS TOSOH CORP (JP) 2014-08-13 EP disclosed
US-8138355-B2 Heteroacene derivative, tetrahaloterphenyl derivative, and processes for producing the same TOSOH CORPORATION (JP) 2012-03-20 US disclosed
EP-2067782-A1 HETEROACENE DERIVATIVE, TETRAHALOTERPHENYL DERIVATIVE, AND THEIR PRODUCTION METHODS Tosoh Corporation (JP) 2009-06-10 EP disclosed
US-20090023957-A1 TERPHENYLENE DERIVATIVE, TETRAHALOTERPHENYL DERIVATIVE, AND PROCESSES FOR PRODUCING BOTH TOSOH CORPORATION (JP) 2009-01-22 US disclosed
US-20090023957-A1 TERPHENYLENE DERIVATIVE, TETRAHALOTERPHENYL DERIVATIVE, AND PROCESSES FOR PRODUCING BOTH TOSOH CORPORATION (JP) 2009-01-22 US disclosed
US-20090023957-A1 TERPHENYLENE DERIVATIVE, TETRAHALOTERPHENYL DERIVATIVE, AND PROCESSES FOR PRODUCING BOTH TOSOH CORPORATION (JP) 2009-01-22 US disclosed
US-7438981-B2 Indenofluorene compounds and organic electroluminescent devices using the same LG. PHILIPS LCD CO., LTD. (KR) 2008-10-21 US disclosed
US-7438981-B2 Indenofluorene compounds and organic electroluminescent devices using the same LG. PHILIPS LCD CO., LTD. (KR) 2008-10-21 US disclosed
EP-1867623-A1 TERPHENYLENE DERIVATIVES, TETRAHALOTERPHENYL DERIVATIVES AND PROCESSES FOR THE PRODUCTION OF BOTH Tosoh Corporation (JP) 2007-12-19 EP disclosed
EP-1867623-A1 TERPHENYLENE DERIVATIVES, TETRAHALOTERPHENYL DERIVATIVES AND PROCESSES FOR THE PRODUCTION OF BOTH Tosoh Corporation (JP) 2007-12-19 EP disclosed
US-20070141389-A1 Indenofluorene compounds and organic electroluminescent devices using the same LG.PHILIPS LCD CO., LTD. (KR) 2007-06-21 US disclosed
US-20070141389-A1 Indenofluorene compounds and organic electroluminescent devices using the same LG.PHILIPS LCD CO., LTD. (KR) 2007-06-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090023957-A1 TERPHENYLENE DERIVATIVE, TETRAHALOTERPHENYL DERIVATIVE, AND PROCESSES FOR PRODUCING BOTH TERT, TLN1, TTI1 ALDH1A1 954/4885MAPK1 2342/4885MAOB 2930/4885
US-20170137566-A1 POLYMER COMPOUND AND LIGHT EMITTING DEVICE USING THE SAME ARL1, NMRAL1, RB1 ALDH1A1 392/4885MAPK1 1498/4885MAOB 3124/4885
US-20070141389-A1 Indenofluorene compounds and organic electroluminescent devices using the same KCNH2, KCNH3, KCNJ2 ALDH1A1 912/4885MAPK1 1325/4885MAOB 2884/4885
US-10370484-B2 Polymer compound and light emitting device using the same ARL1, NMRAL1, RB1 ALDH1A1 392/4885MAPK1 1498/4885MAOB 3124/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.