Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 8/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KLK7 | P49862 | 1/20 | 0.34 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7345858 | 0.92 | KMT2A (0.41) | TRPM8MEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL7337605 | 0.89 | MAPT (0.41) | TRPM8MEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL7345623 | 0.88 | MAPT (0.41) | TRPM8MEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL7344657 | 0.79 | CA12 (0.39) | MEN1KMT2ASMN1; SMN2GAAMAPT | |
| SCHEMBL7342119 | 0.78 | SGMS2 (0.46) | TRPM8MEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL7345667 | 0.76 | DRD2 (0.37) | MEN1KMT2ASMN1; SMN2HPGDMAPK1 | |
| SCHEMBL3454806 | 0.73 | TRPM8 (0.77) | TRPM8MEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL7337600 | 0.72 | RXFP1 (0.38) | MEN1KMT2ASMN1; SMN2GAAMAPT | |
| SCHEMBL7778567 | 0.72 | KDM4E (0.55) | MAPTL3MBTL1POLBMAPK1 | |
| SCHEMBL7337773 | 0.72 | IDO1 (0.37) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832061-B1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| WO-1996041795-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-27 | — | — | WO | disclosed |