Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7342126 | 0.92 | TRPM8 (0.47) | KMT2AMEN1SMN1; SMN2GAAMAPT | |
| SCHEMBL7345623 | 0.91 | MAPT (0.41) | KMT2AMEN1SMN1; SMN2GAAMAPT | |
| SCHEMBL7337605 | 0.89 | MAPT (0.41) | KMT2AMEN1SMN1; SMN2GAAMAPT | |
| SCHEMBL7345849 | 0.78 | MAPT (0.37) | KMT2AMEN1SMN1; SMN2GAAMAPT | |
| SCHEMBL7345667 | 0.74 | DRD2 (0.37) | KMT2AMEN1SMN1; SMN2HPGDHIF1A | |
| SCHEMBL7340053 | 0.74 | SIGMAR1 (0.39) | KMT2AMEN1MAPTTSHRHPGD | |
| SCHEMBL7337600 | 0.73 | RXFP1 (0.38) | KMT2AMEN1SMN1; SMN2GAAMAPT | |
| SCHEMBL7344657 | 0.73 | CA12 (0.39) | KMT2AMEN1SMN1; SMN2GAAMAPT | |
| SCHEMBL7337773 | 0.72 | IDO1 (0.37) | KMT2AMEN1SMN1; SMN2MAPTHPGD | |
| SCHEMBL7346426 | 0.72 | MAPT (0.41) | KMT2AMEN1SMN1; SMN2MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832061-B1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| US-6054457-A | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-25 | — | — | US | disclosed |
| WO-1996041795-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-27 | — | — | WO | disclosed |