Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNF4 | P78317 | 1/20 | 0.47 |
| ▸ | TAS2R14 | Q9NYV8 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.46 |
| ▸ | PTGES | O14684 | 2/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.44 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.44 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7347840 | 0.93 | MAPT (0.50) | RNF4KDM4EALDH1A1LMNACHRM1 | |
| SCHEMBL7349167 | 0.90 | RNF4 (0.59) | RNF4KDM4EALDH1A1LMNACHRM1 | |
| SCHEMBL7343295 | 0.89 | RNF4 (0.46) | RNF4KDM4EALDH1A1LMNACHRM1 | |
| SCHEMBL7346461 | 0.89 | OPRM1 (0.53) | RNF4ALDH1A1CHRM1CHRM3CHRM5 | |
| SCHEMBL7348763 | 0.88 | ALDH1A1 (0.53) | RNF4KDM4EALDH1A1LMNACHRM1 | |
| SCHEMBL7341561 | 0.88 | RNF4 (0.46) | RNF4KDM4EALDH1A1LMNACHRM1 | |
| SCHEMBL7339267 | 0.88 | BCL2A1 (0.57) | RNF4ALDH1A1LMNACHRM1CHRM3 | |
| SCHEMBL7347769 | 0.88 | ALDH1A1 (0.52) | RNF4KDM4EALDH1A1LMNACHRM1 | |
| SCHEMBL7347126 | 0.80 | HDAC1 (0.49) | RNF4ALDH1A1CHRM1CHRM3CHRM5 | |
| SCHEMBL7339248 | 0.79 | KDM4E (0.47) | KDM4EALDH1A1LMNAMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0585500-A1 | Diaryl piperazineacetamides as antimuscarinic agents | MERRELL DOW PHARMACEUTICALS INC. (US) | 1994-03-09 | — | — | EP | disclosed |