Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNF4 | P78317 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.44 |
| ▸ | TSPO | P30536 | 1/20 | 0.44 |
| ▸ | BCL2A1 | Q16548 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | PPIB | P23284 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7347840 | 0.94 | MAPT (0.50) | RNF4MAPTCHRM1CHRM3CHRM5 | |
| SCHEMBL7346461 | 0.90 | OPRM1 (0.53) | RNF4MAPTCHRM1CHRM3CHRM5 | |
| SCHEMBL7343295 | 0.90 | RNF4 (0.46) | RNF4MAPTCHRM1CHRM3CHRM5 | |
| SCHEMBL7347769 | 0.89 | ALDH1A1 (0.52) | RNF4MAPTCHRM1CHRM3CHRM5 | |
| SCHEMBL7339267 | 0.89 | BCL2A1 (0.57) | RNF4MAPTCHRM1CHRM3CHRM5 | |
| SCHEMBL7348763 | 0.89 | ALDH1A1 (0.53) | RNF4MAPTCHRM1CHRM3CHRM5 | |
| SCHEMBL7349167 | 0.89 | RNF4 (0.59) | RNF4CHRM1CHRM3CHRM5LMNA | |
| SCHEMBL7342184 | 0.88 | RNF4 (0.47) | RNF4MAPTCHRM1CHRM3CHRM5 | |
| SCHEMBL7339673 | 0.87 | LMNA (0.46) | LMNAOPRM1ALDH1A1KDM4EMEN1 | |
| SCHEMBL7347126 | 0.87 | HDAC1 (0.49) | RNF4MAPTCHRM1CHRM3CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0585500-A1 | Diaryl piperazineacetamides as antimuscarinic agents | MERRELL DOW PHARMACEUTICALS INC. (US) | 1994-03-09 | — | — | EP | disclosed |