Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | RNF4 | P78317 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MC4R | P32245 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7347840 | 0.94 | MAPT (0.50) | ALDH1A1TSHRKDM4EOPRM1LMNA | |
| SCHEMBL7343295 | 0.90 | RNF4 (0.46) | ALDH1A1TSHRKDM4EOPRM1LMNA | |
| SCHEMBL7346461 | 0.90 | OPRM1 (0.53) | ALDH1A1OPRM1CHRM5CHRM1CHRM3 | |
| SCHEMBL7347769 | 0.89 | ALDH1A1 (0.52) | ALDH1A1TSHRKDM4EOPRM1LMNA | |
| SCHEMBL7341561 | 0.89 | RNF4 (0.46) | ALDH1A1TSHRKDM4EOPRM1LMNA | |
| SCHEMBL7339267 | 0.89 | BCL2A1 (0.57) | ALDH1A1LMNACHRM5CHRM1CHRM3 | |
| SCHEMBL7349167 | 0.89 | RNF4 (0.59) | ALDH1A1TSHRKDM4EOPRM1LMNA | |
| SCHEMBL7342184 | 0.88 | RNF4 (0.47) | ALDH1A1KDM4ELMNACHRM5CHRM1 | |
| SCHEMBL7346787 | 0.87 | ALDH1A1 (0.56) | ALDH1A1TSHRKDM4EOPRM1LMNA | |
| SCHEMBL7350134 | 0.83 | ALDH1A1 (0.52) | ALDH1A1TSHRKDM4EOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0585500-A1 | Diaryl piperazineacetamides as antimuscarinic agents | MERRELL DOW PHARMACEUTICALS INC. (US) | 1994-03-09 | — | — | EP | disclosed |