Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 20/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7808389 | 0.92 | NOTUM (0.66) | NOTUM | |
| SCHEMBL8304573 | 0.69 | HTR3A (0.35) | — | |
| Hydrochloric Acid SCHEMBL8369706 | 0.69 | HTR3A (0.35) | — | |
| SCHEMBL23529336 | 0.69 | NOTUM (0.53) | NOTUM | |
| SCHEMBL30043743 | 0.69 | NOTUM (0.53) | NOTUM | |
| SCHEMBL7808385 | 0.68 | HTR3A (0.34) | — | |
| SCHEMBL15552224 | 0.68 | NOTUM (0.71) | NOTUM | |
| SCHEMBL6961012 | 0.68 | NOTUM (0.44) | NOTUM | |
| Hydrochloric Acid SCHEMBL7945320 | 0.67 | HTR3A (0.34) | — | |
| SCHEMBL4387990 | 0.67 | HTR3A (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975631-B1 | 5-ARYL-3-(8-AZABICYCLO[3.2.1]OCT-3-YL)-1,3,4-OXADIAZOL-2(3H)-ONE DERIVATIVES AS 5-HT4 RECEPTOR LIGANDS | SANOFI SYNTHELABO (FR) | 2001-10-04 | — | — | EP | disclosed |
| US-6255319-B1 | ANTISEROTONIN AGENT | SANOFI-SYNTHELABO (FR) | 2001-07-03 | — | — | US | disclosed |
| US-5929089-A | ANTISEROTONINE AGENT | SYNTHELABO (FR) | 1999-07-27 | — | — | US | disclosed |
| US-5925768-A | ANTIINFLAMMATORY AGENTS; ANALGESICS, ANTICOAGULANTS, NARCOTICS | SANOFI (FR) | 1999-07-20 | — | — | US | disclosed |
| EP-0863897-B1 | 5-PHENYL-3-(PIPERIDIN-4-YL)-1,3,4-OXADIAZOL-2(3H)-ONE DERIVATIVES FOR USE AS 5-HT4- OR H3-RECEPTOR LIGANDS | SYNTHELABO (FR) | 1999-06-16 | — | — | EP | disclosed |
| EP-0863897-A1 | 5-PHENYL-3-(PIPERIDIN-4-YL)-1,3,4-OXADIAZOL-2(3H)-ONE DERIVATIVES FOR USE AS 5-HT 4? OR H 3? RECEPTOR LIGANDS | SYNTHELABO (FR) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997017345-A1 | 5-PHENYL-3-(PIPERIDIN-4-YL)-1,3,4-OXADIAZOL-2(3H)-ONE DERIVATIVES FOR USE AS 5-HT4 OR H3 RECEPTOR LIGANDS | SYNTHELABO (FR) | 1997-05-15 | — | — | WO | disclosed |