Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 19/20 | 0.44 |
| ▸ | PYGL | P06737 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8366393 | 0.82 | NOTUM (0.41) | NOTUM | |
| SCHEMBL8306207 | 0.73 | GPR55 (0.35) | — | |
| SCHEMBL6956244 | 0.72 | FSCN1 (0.33) | — | |
| SCHEMBL7799605 | 0.72 | GPR55 (0.34) | — | |
| SCHEMBL8307581 | 0.71 | GPR55 (0.38) | — | |
| SCHEMBL6958154 | 0.70 | KDM4E (0.45) | NOTUM | |
| SCHEMBL7342200 | 0.68 | NOTUM (0.55) | NOTUM | |
| SCHEMBL8309066 | 0.66 | HTR4 (0.46) | CYP1A2 | |
| SCHEMBL7808389 | 0.66 | NOTUM (0.66) | NOTUM | |
| SCHEMBL8308257 | 0.66 | NR3C1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0980368-B1 | 3-(PYRROLIDIN-3-YL)-1,3,4-OXADIAZOL-2(3H)-ONE DERIVATIVES AND THEIR USE AS 5-HT4 LIGANDS | SANOFI SYNTHELABO (FR) | 2003-10-22 | — | — | EP | disclosed |
| US-6248757-B1 | ANTISEROTONINE AGENTS | SANOFI-SYNTHELABO (FR) | 2001-06-19 | — | — | US | disclosed |
| EP-0863897-B1 | 5-PHENYL-3-(PIPERIDIN-4-YL)-1,3,4-OXADIAZOL-2(3H)-ONE DERIVATIVES FOR USE AS 5-HT4- OR H3-RECEPTOR LIGANDS | SYNTHELABO (FR) | 1999-06-16 | — | — | EP | disclosed |