SCHEMBL8304573

SCHEMBL8304573

O=c1oc(-c2cc(Cl)cc3c2OCC3)nn1C1CCNCC1

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HTR3A P46098 1/20 0.35
HTR2C P28335 8/20 0.33
HTR2A P28223 7/20 0.33
HTR2B P41595 1/20 0.33
GPR55 Q9Y2T6 2/20 0.33
CNR1 P21554 2/20 0.32
NSD3 Q9BZ95 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8369706 0.99 HTR3A (0.35) HTR3AHTR2CHTR2AHTR2BGPR55
SCHEMBL8304451 0.94 NOTUM (0.38) HTR2CHTR2AHTR2BGPR55CNR1
Hydrochloric Acid SCHEMBL8366408 0.93 NOTUM (0.37) HTR2CHTR2AHTR2BGPR55CNR1
SCHEMBL7808385 0.85 HTR3A (0.34) HTR3AGPR55
Hydrochloric Acid SCHEMBL7945320 0.85 HTR3A (0.34) HTR3AGPR55
SCHEMBL8304883 0.81 HTR4 (0.35) HTR3AHTR2CHTR2AHTR2B
SCHEMBL8303784 0.80 NR3C1 (0.39) GPR55CNR1
SCHEMBL7810013 0.80 NOTUM (0.36) HTR2CHTR2AHTR2BGPR55CNR1
Hydrochloric Acid SCHEMBL7946657 0.79 NOTUM (0.36) GPR55CNR1
SCHEMBL8308109 0.79 HTR4 (0.48) HTR3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5929089-A ANTISEROTONINE AGENT SYNTHELABO (FR) 1999-07-27 US disclosed
EP-0863897-B1 5-PHENYL-3-(PIPERIDIN-4-YL)-1,3,4-OXADIAZOL-2(3H)-ONE DERIVATIVES FOR USE AS 5-HT4- OR H3-RECEPTOR LIGANDS SYNTHELABO (FR) 1999-06-16 EP disclosed