SCHEMBL7808385

SCHEMBL7808385

O=c1oc(-c2cc(Cl)cc3c2OCC3)nn1C1CC2CCC(C1)N2

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTR3A P46098 1/20 0.34
GPR55 Q9Y2T6 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7945320 0.99 HTR3A (0.34) HTR3AGPR55
SCHEMBL7810013 0.94 NOTUM (0.36) GPR55
Hydrochloric Acid SCHEMBL7946657 0.93 NOTUM (0.36) GPR55
SCHEMBL8304573 0.85 HTR3A (0.35) HTR3AGPR55
Hydrochloric Acid SCHEMBL8369706 0.84 HTR3A (0.35) HTR3AGPR55
SCHEMBL7804890 0.80 HTR4 (0.46) HTR3A
SCHEMBL8304451 0.80 NOTUM (0.38) GPR55
Hydrochloric Acid SCHEMBL8366408 0.79 NOTUM (0.37) GPR55
Hydrochloric Acid SCHEMBL7945299 0.79 HTR4 (0.46) HTR3A
SCHEMBL7810030 0.78 HRH3 (0.37) GPR55

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0975631-B1 5-ARYL-3-(8-AZABICYCLO[3.2.1]OCT-3-YL)-1,3,4-OXADIAZOL-2(3H)-ONE DERIVATIVES AS 5-HT4 RECEPTOR LIGANDS SANOFI SYNTHELABO (FR) 2001-10-04 EP disclosed