SCHEMBL734280

SCHEMBL734280

Ic1cc2ccccc2s1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 4/20 0.50
ASIC3 Q9UHC3 1/20 0.50
LOXL2 Q9Y4K0 1/20 0.50
MGLL Q99685 1/20 0.50
BCL2L1 Q07817 1/20 0.48
CA2 P00918 2/20 0.47
APP P05067 2/20 0.45
AGXT P21549 1/20 0.45
ADRB2 P07550 1/20 0.45
HDAC3 O15379 1/20 0.45
HDAC4 P56524 1/20 0.45
HDAC1 Q13547 1/20 0.45
HDAC7 Q8WUI4 1/20 0.45
HDAC2 Q92769 1/20 0.45
HDAC10 Q969S8 1/20 0.45
HDAC11 Q96DB2 1/20 0.45
HDAC8 Q9BY41 1/20 0.45
HDAC6 Q9UBN7 1/20 0.45
HDAC9 Q9UKV0 1/20 0.45
HDAC5 Q9UQL6 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17666747 0.80 ALDH1A1 (0.34) CYP2A6ASIC3LOXL2MGLLBCL2L1
SCHEMBL27745383 0.77 APP (0.49) CYP2A6ASIC3LOXL2MGLLBCL2L1
SCHEMBL845603 0.76 APP (0.63) CYP2A6ASIC3LOXL2MGLLBCL2L1
SCHEMBL29732980 0.76 APP (0.63) CYP2A6ASIC3LOXL2MGLLBCL2L1
SCHEMBL2149703 0.73 APP (0.50) CYP2A6ASIC3LOXL2MGLLBCL2L1
SCHEMBL17394561 0.72 AGXT (0.48) CYP2A6ASIC3LOXL2MGLLBCL2L1
SCHEMBL6443895 0.72 CYP2A6 (0.48) CYP2A6ASIC3LOXL2MGLLBCL2L1
SCHEMBL21322484 0.72 CYP2A6 (0.48) CYP2A6ASIC3LOXL2MGLLBCL2L1
SCHEMBL21177766 0.72 CYP2A6 (0.48) CYP2A6ASIC3LOXL2MGLLBCL2L1
SCHEMBL6651277 0.72 CYP2A6 (0.48) CYP2A6ASIC3LOXL2MGLLBCL2L1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 156 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4482583-B1 ZWITTERIONIC ANTIBACTERIAL COMPOUNDS HOFFMANN LA ROCHE (CH) 2026-04-01 EP disclosed
EP-4680677-A1 BENZOTHIENOPYRROLE CYANINE DYES Beckman Coulter, Inc. (US) 2026-01-21 EP disclosed
US-12478621-B2 Substituted aminoquinolones as dgkalpha inhibitors for immune activation DEUTSCHES KREBSFORSCHUNGSZENTRUM (DE) 2025-11-25 US disclosed
US-20250179066-A1 ZWITTERIONIC ANTIBACTERIAL COMPOUNDS HOFFMANN-LA ROCHE INC. (US) 2025-06-05 US disclosed
CN-119661526-A Perylene imide compound and preparation method and application thereof 华东理工大学 2025-03-21 CN disclosed
CN-119564686-A DGK alpha inhibitors as immune activation substituted aminoquinolones of (2) 拜耳公司 2025-03-07 CN disclosed
CN-119523983-A DGK alpha inhibitors as immune activation substituted aminoquinolones of (2) 拜耳公司 2025-02-28 CN disclosed
CN-119424429-A DGK alpha inhibitors as immune activation substituted aminoquinolones of (2) 拜耳公司 2025-02-14 CN disclosed
WO-2025021855-A1 MATERIALS FOR ORGANIC LIGHT-EMITTING DEVICES AND ORGANIC SENSORS MERCK PATENT GMBH (DE) 2025-01-30 WO disclosed
EP-4482583-A1 ZWITTERIONIC ANTIBACTERIAL COMPOUNDS F. Hoffmann-La Roche AG (CH) 2025-01-01 EP disclosed
CN-1252138-A Ternary photoinitiator system for curing of epoxy resins MINNESOTA MINING & MFG (US) 2000-05-03 CN disclosed
CN-1197817-A Ink jet print head containing radiation curable resin layer LEXMARK INT INC (US) 1998-11-04 CN disclosed
US-5464865-A Enzyme inhibitors as antiinflammatory agents ORTHO PHARMACEUTICAL CORPORATION (US) 1995-11-07 US disclosed
EP-0538310-B1 ETHYNYLBENZOTHIOPHENE PESTICIDES FMC CORP (US) 1995-09-13 EP disclosed
US-5248686-A Treatment of nervous depression CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 1993-09-28 US disclosed
EP-0538310-A4 ETHYNYLBENZOTHIOPHENE PESTICIDES 1993-07-14 EP disclosed
EP-0538310-A1 ETHYNYLBENZOTHIOPHENE PESTICIDES. FMC CORP (US) 1993-04-28 EP disclosed
WO-1992000672-A1 ETHYNYLBENZOTHIOPHENE PESTICIDES FMC CORPORATION (US) 1992-01-23 WO disclosed
US-5073564-A Photoactivated insecticides FMC CORPORATION (US) 1991-12-17 US disclosed
US-4758639-A Process for production of vinyl polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250179066-A1 ZWITTERIONIC ANTIBACTERIAL COMPOUNDS MRPL21, WIZ, CFTR CYP2A6 2634/4885ASIC3 271/4885LOXL2 4587/4885
US-12478621-B2 Substituted aminoquinolones as dgkalpha inhibitors for immune activation DGKK, DGKG, DGKA CYP2A6 2795/4885ASIC3 3800/4885LOXL2 4646/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.