Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4Z1 | Q86W10 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.34 |
| ▸ | LIPE | Q05469 | 1/20 | 0.34 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7345259 | 0.88 | CYP4Z1 (0.51) | CYP4Z1MAPTLMNASMN1; SMN2CTDSP1 | |
| SCHEMBL7337806 | 0.82 | CA12 (0.44) | MAPTLMNASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL7346077 | 0.81 | CYP4Z1 (0.45) | CYP4Z1MAPTLMNASMN1; SMN2CTDSP1 | |
| SCHEMBL7339360 | 0.81 | ALDH1A1 (0.52) | CYP4Z1MAPTSMN1; SMN2CTDSP1ALDH1A1 | |
| SCHEMBL16774519 | 0.73 | TBXAS1 (0.50) | CYP4Z1MAPTLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL68851 | 0.72 | CYP4Z1 (0.62) | CYP4Z1MAPTLMNASMN1; SMN2TSHR | |
| SCHEMBL7343265 | 0.71 | MAPT (0.54) | CYP4Z1MAPTLMNASMN1; SMN2TSHR | |
| SCHEMBL512626 | 0.71 | CYP4Z1 (0.55) | CYP4Z1MAPTLMNASMN1; SMN2TSHR | |
| SCHEMBL7343260 | 0.70 | MAPT (0.51) | CYP4Z1MAPTLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL24095167 | 0.70 | CYP4Z1 (0.50) | CYP4Z1MAPTLMNASMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5622984-A | INHIBITORS OF PHOSPHOLIPASE, VARIOUS PROTEASES | ONO PHARMACEUTICAL COMPANY, LIMITED (JP) | 1997-04-22 | — | — | US | disclosed |
| US-5614555-A | Amidinophenol derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1997-03-25 | — | — | US | disclosed |
| EP-0588655-B1 | Amidinophenol derivatives | ONO PHARMACEUTICAL CO (JP) | 1996-12-04 | — | — | EP | disclosed |
| US-5432178-A | Substituted benzoic acid esters; use to prevent or treat inflammatory diseases, allergic diseases, disseminated intravascular coagulation, pancreatitis or multiple organ failure | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-07-11 | — | — | US | disclosed |
| EP-0588655-A1 | Amidinophenol derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-03-23 | — | — | EP | disclosed |