Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | MITF | O75030 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CDK4 | P11802 | 1/20 | 0.40 |
| ▸ | CCND1 | P24385 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MC5R | P33032 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7334283 | 0.88 | ALDH1A1 (0.62) | ALDH1A1NPC1RAB9AMEN1MITF | |
| SCHEMBL4790366 | 0.81 | ALDH1A1 (0.52) | ALDH1A1NPC1RAB9AMEN1MITF | |
| SCHEMBL7344048 | 0.77 | FLT1 (0.40) | ALDH1A1NPC1RAB9AMEN1MITF | |
| SCHEMBL20334886 | 0.76 | NPC1 (1.00) | ALDH1A1NPC1RAB9AMEN1MITF | |
| SCHEMBL7335255 | 0.74 | CYP2A6 (0.38) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL7343077 | 0.73 | SLC6A2 (0.47) | ALDH1A1NPC1RAB9AMEN1MITF | |
| SCHEMBL23094166 | 0.73 | NPC1 (1.00) | ALDH1A1NPC1RAB9AMEN1MITF | |
| SCHEMBL21467691 | 0.73 | MAPT (0.81) | ALDH1A1NPC1RAB9AMEN1MITF | |
| SCHEMBL13475466 | 0.73 | ALDH1A1 (0.70) | ALDH1A1NPC1RAB9AMEN1MITF | |
| SCHEMBL7344328 | 0.72 | NPC1 (0.46) | ALDH1A1NPC1RAB9AMEN1MITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5177088-A | Cognition Activators | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1993-01-05 | — | — | US | claimed |
| EP-0509402-B1 | Substituted 3-(Pyridinylamino)-indoles and benzo[b]thiophenes, a process for their preparation and their use as medicaments | HOECHST MARION ROUSSEL INC (US) | 1998-01-07 | — | — | EP | disclosed |
| US-5177088-A | Cognition Activators | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1993-01-05 | — | — | US | disclosed |
| EP-0509402-A1 | Substituted 3-(Pyridinylamino)-indoles and benzo[b]thiophenes, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1992-10-21 | — | — | EP | disclosed |