Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | MITF | O75030 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
| ▸ | CCND1 | P24385 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4820134 | 0.83 | NPC1 (0.43) | ALDH1A1NPC1RAB9AMEN1MITF | |
| SCHEMBL7334283 | 0.82 | ALDH1A1 (0.62) | ALDH1A1NPC1RAB9AMEN1MITF | |
| SCHEMBL7343483 | 0.81 | ALDH1A1 (0.61) | ALDH1A1NPC1RAB9AMEN1MITF | |
| SCHEMBL7343077 | 0.71 | SLC6A2 (0.47) | ALDH1A1NPC1RAB9AMEN1MITF | |
| SCHEMBL20334886 | 0.69 | NPC1 (1.00) | ALDH1A1NPC1RAB9AMEN1MITF | |
| SCHEMBL7671956 | 0.67 | ALDH1A1 (0.44) | ALDH1A1NPC1RAB9AMEN1MITF | |
| SCHEMBL6394938 | 0.66 | ALDH1A1 (0.56) | ALDH1A1NPC1RAB9AMEN1MITF | |
| SCHEMBL23094166 | 0.66 | NPC1 (1.00) | ALDH1A1NPC1RAB9AMEN1MITF | |
| SCHEMBL21467691 | 0.66 | MAPT (0.81) | ALDH1A1NPC1RAB9AMEN1MITF | |
| SCHEMBL13475466 | 0.66 | ALDH1A1 (0.70) | ALDH1A1NPC1RAB9AMEN1MITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008157740-A2 | FAAH INHIBITORS | IRONWOOD PHARMACEUTICALS, INC. (US) | 2008-12-24 | — | — | WO | disclosed |