Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PTPRB | P23467 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.32 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.32 |
| ▸ | TUBB | P07437 | 1/20 | 0.32 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7346501 | 0.81 | ALDH1A1 (0.45) | ALDH1A1RECQLMAPK1PKMKDM4E | |
| SCHEMBL7352286 | 0.77 | ALDH1A1 (0.39) | ALDH1A1KDM4ETHRBPTPRBTDP1 | |
| SCHEMBL7348321 | 0.77 | ALDH1A1 (0.40) | ALDH1A1KDM4ETHRBTDP1THRA | |
| SCHEMBL7344143 | 0.76 | ALDH1A1 (0.33) | ALDH1A1MAPK1KDM4ETHRBHTT | |
| SCHEMBL7344148 | 0.76 | KMT2A (0.40) | ALDH1A1KDM4ETHRBTDP1THRA | |
| SCHEMBL2688605 | 0.73 | ALDH1A1 (0.64) | ALDH1A1RECQLMAPK1PKMKDM4E | |
| SCHEMBL7353139 | 0.73 | THRB (0.40) | ALDH1A1KDM4ETHRBTDP1THRA | |
| SCHEMBL7281994 | 0.70 | ALDH1A1 (0.41) | ALDH1A1RECQLMAPK1PKMKDM4E | |
| SCHEMBL7351856 | 0.70 | RORC (0.38) | ALDH1A1RECQLMAPK1PKMKDM4E | |
| SCHEMBL5366575 | 0.70 | ALDH1A1 (0.62) | ALDH1A1RECQLMAPK1PKMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5284971-A | No cardiac side effects | SYNTEX (U.S.A.) INC. (US) | 1994-02-08 | — | — | US | disclosed |