Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PTPRB | P23467 | 2/20 | 0.37 |
| ▸ | RORC | P51449 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | ACP1 | P24666 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7351856 | 0.89 | RORC (0.38) | ALDH1A1RECQLMAPK1RORCCA1 | |
| SCHEMBL7344141 | 0.81 | ALDH1A1 (0.46) | ALDH1A1RECQLMAPK1PTPRBRORC | |
| SCHEMBL7348710 | 0.77 | ALDH1A1 (0.41) | ALDH1A1MAPK1PTPRBRORCCA1 | |
| SCHEMBL7343576 | 0.77 | ALDH1A1 (0.42) | ALDH1A1MAPK1RORCLMNATSHR | |
| SCHEMBL7346507 | 0.77 | ALDH1A1 (0.36) | ALDH1A1RORCCA12CA1CA2 | |
| SCHEMBL7346510 | 0.76 | KMT2A (0.37) | ALDH1A1RORCCA12CA1CA2 | |
| SCHEMBL7350727 | 0.76 | NR3C1 (0.46) | ALDH1A1MAPK1RORCTSHRPKM | |
| SCHEMBL2688605 | 0.72 | ALDH1A1 (0.64) | ALDH1A1RECQLMAPK1PTPRBCA12 | |
| SCHEMBL7351859 | 0.72 | ALDH1A1 (0.38) | ALDH1A1RORCLMNATSHRPKM | |
| SCHEMBL7351863 | 0.71 | KMT2A (0.41) | ALDH1A1RORCTSHRPKMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5284971-A | No cardiac side effects | SYNTEX (U.S.A.) INC. (US) | 1994-02-08 | — | — | US | disclosed |