Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 2/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 2/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | CCR2 | P41597 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7344227 | 0.84 | HTT (0.40) | HTTL3MBTL1MEN1KMT2AEPHX2 | |
| SCHEMBL7340024 | 0.79 | ALDH1A1 (0.39) | HTTL3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL7338177 | 0.77 | TTR (0.43) | HTTL3MBTL1MEN1KMT2AGAA | |
| SCHEMBL7344206 | 0.77 | HTT (0.48) | HTTL3MBTL1MEN1KMT2AEPHX2 | |
| SCHEMBL7343748 | 0.77 | MEN1 (0.46) | HTTL3MBTL1MEN1KMT2AGAA | |
| SCHEMBL7340904 | 0.76 | F10 (0.46) | HTTL3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL7339143 | 0.76 | RXFP1 (0.48) | HTTL3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL6773153 | 0.76 | ITGB3 (0.55) | HTTL3MBTL1MEN1KMT2AEPHX2 | |
| SCHEMBL7343738 | 0.76 | PLK4 (0.47) | HTTL3MBTL1MEN1KMT2AGAA | |
| SCHEMBL7372871 | 0.76 | PLK4 (0.50) | MEN1KMT2AALDH1A1GAARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850221-A1 | META-GUANIDINE, UREA, THIOUREA OR AZACYCLIC AMINO BENZOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1998-07-01 | — | — | EP | claimed |
| WO-1997008145-A1 | META-GUANIDINE, UREA, THIOUREA OR AZACYCLIC AMINO BENZOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1997-03-06 | — | — | WO | claimed |