Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ2 | O43526 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.45 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.45 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.43 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.42 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4682762 | 0.78 | AVPR1A (0.64) | AVPR1AAVPR1BAVPR2 | |
| SCHEMBL7365651 | 0.77 | AVPR1A (0.67) | AVPR1AAVPR2 | |
| SCHEMBL6986447 | 0.77 | AVPR1A (0.71) | KCNQ2THRBKCNJ5KCNJ3AVPR1A | |
| SCHEMBL8561675 | 0.77 | NAMPT (0.50) | KCNQ2THRBKCNJ5KCNJ3AVPR1A | |
| SCHEMBL7344301 | 0.76 | THRB (0.49) | KCNQ2THRBKCNJ5KCNJ3AVPR1A | |
| SCHEMBL6987453 | 0.76 | AVPR1A (0.62) | KCNQ2THRBAVPR1AAVPR1BAVPR2 | |
| SCHEMBL8318866 | 0.75 | KCNJ5 (0.47) | KCNQ2THRBKCNJ5KCNJ3AVPR2 | |
| SCHEMBL7340964 | 0.74 | KCNJ5 (0.48) | KCNQ2THRBKCNJ5KCNJ3SMN1; SMN2 | |
| SCHEMBL8559196 | 0.74 | THRB (0.55) | THRBKCNJ5KCNJ3 | |
| SCHEMBL8556372 | 0.74 | KCNJ5 (0.51) | KCNQ2THRBKCNJ5KCNJ3AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5244898-A | Vasopressin antagonist | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-09-14 | — | — | US | disclosed |
| EP-0514667-A1 | Benzazepin derivatives as vasopressin antagonists | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-25 | — | — | EP | disclosed |